MABF240

Anti-hGITR Antibody, clone 108-17

clone 108-17, from mouse

• Synonim(y): Tumor necrosis factor receptor superfamily member 18, Activation-inducible TNFR family receptor, Glucocorticoid-induced TNFR-related protein, CD357
• Kod UNSPSC: 12352203
• eCl@ss: 32160702
• NACRES: NA.41
• klon: 108-17, monoclonal
• application: WB
• reaktywność gatunkowa: mouse, human, rat
• metody: western blot: suitable

Właściwości

• pochodzenie biologiczne: mouse
• Poziom jakości: 100
• forma przeciwciała: purified immunoglobulin
• rodzaj przeciwciała: primary antibodies
• klon: 108-17, monoclonal
• reaktywność gatunkowa: mouse, human, rat
• metody: western blot: suitable
• izotyp: IgG1κ
• numer dostępu NCBI: NP_004186
• numer dostępu UniProt: Q9Y5U5
• Warunki transportu: wet ice
• docelowa modyfikacja potranslacyjna: unmodified
• informacje o genach: human ... TNFRSF18(8784)

Opis

Opis ogólny

Glucocorticoid-induced TNFR-related protein (hGITR) is also called Tumor necrosis factor receptor superfamily member 18 (TNFRSF18), Activation-inducible TNFR family receptor (AITR) and CD357. hGITR is a receptor for TNFSF18 and is activated by NF-kappa-B through the TRAF2/NIK pathway. hGITR is thought to be involved in activated T-lymphocyte and endothelial cell interactions, as well as regulation of T-cell receptor-mediated cell death. hGITR is expressed in lymph node, peripheral blood leukocytes and at low levels in the spleen.

Immunogen

Recombinant protein corresponding to human hGITR.

Zastosowanie

Anti-hGITR Antibody, clone 108-17 is a highly specific mouse monoclonal antibody & that targets GITR & has been tested in western blotting.

Research Category
Inflammation & Immunology

Research Sub Category
Immunoglobulins & Immunology

Western Blotting Analysis: 1.0 µg/mL from a representative lot detected hGITR in 10 µg of mouse lymph node, rat spleen, and rat thymus tissue lysate.

Jakość

Evaluated by Western Blotting in human spleen tissue lysate.

Western Blotting Analysis: 1.0 µg/mL of this antibody detected hGITR in 10 µg of human spleen tissue lysate.

Opis wartości docelowych

~ 26 kDa observed. Multiple bands can be observed due to GITR being a monomer & homeodimer in some lysates. Uncharacterized band(s) may appear in some lysates.

Postać fizyczna

Format: Purified

Protein A purified

Purified mouse monoclonal IgG1κ in buffer containing PBS with 0.05% sodium azide.

Przechowywanie i stabilność

Stable for 1 year at 2-8°C from date of receipt.

Inne uwagi

Concentration: Please refer to the Certificate of Analysis for the lot-specific concentration.

Oświadczenie o zrzeczeniu się odpowiedzialności

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

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Informacja o środkach bezpieczeństwa

• Kod klasy składowania: 10 - Combustible liquids
• Klasa zagrożenia wodnego (WGK): WGK 2
• Temperatura zapłonu (°F): Not applicable
• Temperatura zapłonu (°C): Not applicable