700121P

sitostanol

β-sitostanol, powder

• Synonim(y): stigmastanol; dihydrositosterol; (3β)-stigmastan-3-ol; (3β,5α)-stigmastan-3-ol
• Wzór empiryczny (zapis Hilla): C₂₉H₅₂O
• Numer CAS: 83-45-4
• Masa cząsteczkowa: 416.72
• Kod UNSPSC: 12352211
• NACRES: NA.25

Właściwości

• Próba: >99% (TLC)
• Postać: powder
• opakowanie: pkg of 1 × 5 mg (700121P-5mg)
• producent / nazwa handlowa: Avanti Research^™ - A Croda Brand 700121P
• Warunki transportu: dry ice
• temp. przechowywania: −20°C
• InChI: 1S/C29H52O/c1-7-21(19(2)3)9-8-20(4)25-12-13-26-24-11-10-22-18-23(30)14-16-28(22,5)27(24)15-17-29(25,26)6/h19-27,30H,7-18H2,1-6H3/t20-,21-,22+,23+,24+,25-,26+,27+,28+,29-/m1/s1
• Klucz InChI: LGJMUZUPVCAVPU-HRJGVYIJSA-N

Opis

Opis ogólny

It is predominantly present in pine oil.

Sitostanol is a 5α-saturated sitosterol derivative.

Sitostanol is a plant stanol and a hydrogenated form of sitosterol.

Zastosowanie

Sitostanol is suitable for its use as a component in micelle preparation, used for cell culture and cellular uptake studies. It is also suitable for use in cell culture to study its effect on a T-helper-1 shift in peripheral blood mononuclear cells (PBMCs) from asthma patients.

Sitostanol may be used in the preparation of binary phospholipid for thermodynamic studies and Brewster angle microscopy studies. It may also be used as a standard steroid in gas chromatography-mass spectrometry(GC-MS).

Działania biochem./fizjol.

Plant stanols are structurally similar to cholesterol, hence it reduces the plasma level of LDL cholesterol. Sitostanol is known to possess hypolipidemic and antiatherogenic effects.

Sitostanol decreases cholesterol absorption. Its ratio with cholesterol is implicated in non-alcoholic fatty liver disease (NAFLD). The ratio also correlates with liver steatosis and inflammation. Sitostanol induces interferon γ production and T-helper response in peripheral blood mononuclear cells (PBMC) in asthma patients. It is a hypocholestremic agent as it decreases the micellar solubility and absorption of cholesterol.

Sitostanol lowers the intestinal absorption of cholesterol and serum cholesterol.

Opakowanie

5 mL Amber Glass Screw Cap Vial (700121P-5mg)

Informacje prawne

Avanti Research is a trademark of Avanti Polar Lipids, LLC

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Informacja o środkach bezpieczeństwa

• Kod klasy składowania: 11 - Combustible Solids