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279315

Sigma-Aldrich

Sodium acetate-2-13C

99 atom % 13C

Synonim(y):

Acetic-2-13C acid sodium salt

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About This Item

Wzór liniowy:
13CH3CO2Na
Numer CAS:
13291-89-9
Masa cząsteczkowa:
83.03
Beilstein:
4211334
Numer MDL:
MFCD00037668
Kod UNSPSC:
12142200
Identyfikator substancji w PubChem:
24856877
NACRES:
NA.12

czystość izotopowa

99 atom % 13C

Poziom jakości

200

Postać

solid

metody

bio NMR: suitable
protein expression: suitable

mp

>300 °C (dec.) (lit.)

przesunięcie masy

M+1

ciąg SMILES

[Na+].[13CH3]C([O-])=O

InChI

1S/C2H4O2.Na/c1-2(3)4;/h1H3,(H,3,4);/q;+1/p-1/i1+1;

Klucz InChI

VMHLLURERBWHNL-YTBWXGASSA-M

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Opis ogólny

Sodium acetate-2-13C is 13C isotopomer labeled precursor of sodium acetate.

Zastosowanie

13C labeling in the methyl group has a significant effect on the Dynamic Nuclear Polarization of acetate. Sodium acetate-2-13C labeling can be used in structural studies analyzing the interactions between lipo oligosaccharide and host proteins. Incorporation of Sodium acetate-2-13C shows enriched 13C-NMR spectra indicating their biosynthesis of microbial products and novel polyketides. Hyperpolarized 13C-acetate MRI has been applied to examinations of both rodents and porcine models.

Opakowanie

This product may be available from bulk stock and can be packaged on demand. For information on pricing, availability and packaging, please contact Stable Isotopes Customer Service.
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Kod klasy składowania

11 - Combustible Solids

Klasa zagrożenia wodnego (WGK)

WGK 1

Temperatura zapłonu (°F)

Not applicable

Temperatura zapłonu (°C)

Not applicable

Wybierz jedną z najnowszych wersji:

Certyfikaty analizy (CoA)

Lot/Batch Number
MBBD0985
MBBC8065
MBBC5981
MBBC5088
MBBC2803

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Dokumenty związane z niedawno zakupionymi produktami zostały zamieszczone w Bibliotece dokumentów.

Odwiedź Bibliotekę dokumentów

Deborah M B Post et al.
Journal of endotoxin research, 12(2), 93-98 (2006-05-13)
The lipooligosaccharide (LOS) of a Neisseria meningitidis acetate auxotroph was metabolically labeled with either [2-13C]-sodium acetate or [1,2-13C2]-sodium acetate. In this study, we demonstrated that this label was efficiently incorporated into both the lipid A acyl moieties and the two
Randy Lee Tyson et al.
Brain research, 992(1), 43-52 (2003-11-08)
[1-13C]Glucose, [2-13C]acetate and [3-13C]lactate were infused into male Sprague-Dawley rats (150-170 g) for periods of 3-100 min (n=4 per time) and neocortex extracts were analyzed using 13C-edited 1H magnetic resonance (MR) spectroscopy. The time dependence of the [4-13C]glutamine/[4-13C]glutamate labeling ratio
Emmeli F R Mikkelsen et al.
Scientific reports, 7(1), 16002-16002 (2017-11-24)
11C-acetate is a positron emission tomography (PET) tracer of oxidative metabolism, whereas hyperpolarized 13C-acetate can be used in magnetic resonance imaging (MRI) for investigating specific metabolic processes. The aims of this study were to examine if the kinetic formalism of
Fayrouz El Maddah et al.
Organic & biomolecular chemistry, 17(10), 2747-2752 (2019-02-21)
The marilones and marilines are a new family of polyketide metabolites recently isolated from the marine-derived fungus Stachylidium sp. 293K04. They are characterized by a phthalide and phthalimidine skeleton, respectively. From a series of feeding experiments using 13C-labeled precursors we
Peter Niedbalski et al.
The journal of physical chemistry. A, 121(17), 3227-3233 (2017-04-20)
Dynamic nuclear polarization (DNP) via the dissolution method has alleviated the insensitivity problem in liquid-state nuclear magnetic resonance (NMR) spectroscopy by amplifying the signals by several thousand-fold. This NMR signal amplification process emanates from the microwave-mediated transfer of high electron

Produkty

¹³ C MRS to Probe Brain Metabolism Using Hyperpolarized Pyruvic Acid

We present an article about the hyperpolarization of 13C labeled metabolites, especially pyruvic acid, using dynamic nuclear polarization (DNP) that allows real-time magnetic resonance spectroscopy.

Dynamic Nuclear Polarization

Dynamic Nuclear Polarization (DNP) is a phenomenon by which high spin polarization, typically derived from a bath of free radical electrons, is transferred to a nuclear spin bath, enhancing the difference between the nuclear energy levels and thereby producing dramatically enhanced NMR signals for detection.

MRI/MRS: Use of Isotopes in Hyperpolarization

Sigma-Aldrich.com presents an article concerning MRI/MRS and the use of isotopes in hyperpolarization.

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