T3564

Tumor Necrosis Factor Soluble Receptor I (TNF sRI) from mouse

>97% (SDS-PAGE), recombinant, expressed in E. coli, lyophilized powder, suitable for cell culture

• MDL番号: MFCD01324859
• UNSPSCコード: 51111800
• NACRES: NA.32

特性

• 由来生物: mouse
• 品質水準: 200
• リコンビナント: expressed in E. coli
• アッセイ: >97% (SDS-PAGE)
• 形状: lyophilized powder
• 有効性: 0.5-1.5 μg/mL ED₅₀
• 分子量: 21 kDa
• 包装: pkg of 50 μg
• 保管条件: avoid repeated freeze/thaw cycles
• テクニック: cell culture | mammalian: suitable
• 不純物: endotoxin, tested
• UniProtアクセッション番号: P06804
• 保管温度: −20°C
• 遺伝子情報: mouse ... Tnfrsf1a(21937)

詳細

アプリケーション

Tumor Necrosis Factor Soluble Receptor I (TNF sRI) from mouse plays a pivotal role in the signaling of apoptosis and NF-κB activation because of its “death domain” present at the intracellular portion.

生物化学的／生理学的作用

Tumor Necrosis Factor Soluble Receptor I (TNF sRI) from mouse belongs to TNF family of receptors and has a pivotal role in neutralizing the biological activities of both TNF-α and TNF-β. Soluble tumor necrosis factor receptor along with intrathecal interleukin-1 receptor antagonist shows an anti-allodynic action in rat L5 spinal nerve transection model of neuropathic pain.

物理的形状

Lyophilized from a 0.2 μm filtered solution in phosphate buffered saline with 2.5 mg bovine serum albumin

アナリシスノート

The biological activity is measured by its ability to inhibit the recombinant mouse TNF-α mediated cytotoxicity in mouse L929 cells, in the presence of the metabolic inhibitor actinomycin D.

安全性情報

• 保管分類コード: 11 - Combustible Solids
• WGK: WGK 3
• 引火点(°F): Not applicable
• 引火点(℃): Not applicable