SML0651

OAC1

≥98% (HPLC)

• 別名: N-1H-Pyrrolo[2,3-c]pyridin-5-yl-benzamide
• 実験式（ヒル表記法）: C₁₄H₁₁N₃O
• CAS番号: 300586-90-7
• 分子量: 237.26
• UNSPSCコード: 12352200
• NACRES: NA.77

特性

• アッセイ: ≥98% (HPLC)
• フォーム: powder
• 色: white to beige
• 溶解性: DMSO: 20 mg/mL, clear
• 保管温度: 2-8°C
• SMILES記法: [nH]1c2c(cc1)cc(nc2)NC(=O)c3ccccc3
• InChI: 1S/C14H11N3O/c18-14(10-4-2-1-3-5-10)17-13-8-11-6-7-15-12(11)9-16-13/h1-9,15H,(H,16,17,18)
• InChI Key: HWJRIFZDXJKJJN-UHFFFAOYSA-N

詳細

生物化学的／生理学的作用

OAC1 enhances iPSC reprogramming efficiency by enhancing Oct4 and Nanog driven gene expression.

OAC1 enhances iPSC reprogramming efficiency by enhancing Oct4 and Nanog driven gene expression. Treatment of mouse embryonic fibroblasts transduced with Oct2, Sox2, Klf4 and c-myc displayed a two-fold increase in the formation of ESC-like clones. OAC1 treated cells display a hypomethylated state of Oct4 promoter DNA.

安全性情報

• 保管分類コード: 11 - Combustible Solids
• WGK: WGK 3
• 引火点(°F): Not applicable
• 引火点(℃): Not applicable