H6916

マクロファージコロニー刺激因子 ヒト

≥95% (SDS-PAGE), recombinant, expressed in HEK 293 cells, lyophilized powder, suitable for cell culture

• 別名: MCSF
• MDL番号: MFCD00166591
• UNSPSCコード: 12352202
• NACRES: NA.77

特性

• 製品名: マクロファージコロニー刺激因子 ヒト, M-CSF, recombinant, expressed in HEK 293 cells, suitable for cell culture
• 由来生物: human
• 品質水準: 100
• リコンビナント: expressed in HEK 293 cells
• アッセイ: ≥95% (SDS-PAGE)
• フォーム: lyophilized powder
• 有効性: ≤4 ng/mL EC₅₀
• 品質: endotoxin tested
• 分子量: dimer 35-40 kDa (glycosylated)
• 包装: pkg of 10 μg
• メーカー／製品名: HumanZyme
• テクニック: cell culture | mammalian: suitable
• UniProtアクセッション番号: P09603
• 保管温度: −20°C
• 遺伝子情報: human ... CSF1(1435)

詳細

詳細

M-CSF is encoded by the gene mapped to human chromosome 1p13.3. It is a glycosylated polypeptide, which exists as a homodimer. M-CSF is produced by macrophage, fibroblasts, lymphocyte and endothelial cells.

生物化学的／生理学的作用

Macrophage CSF (M-CSF) as a growth factor, stimulates the proliferation and differentiation of monocyte/macrophage-lineage cells. It also boosts antibody-dependent, cell-mediated cytotoxicity by monocytes and macrophages. In addition, human M-CSF inhibits bone resorption by osteoclasts. It might also play a crucial role in atherosclerosis. Overexpression of the gene has been observed in Paget′s disease of bone (PDB).

物理的形状

Lyophilized from a 0.2 μm filtered solution of 1x PBS.

アナリシスノート

特異的活性は、マウスM-NFS-60細胞(マウス骨髄性白血病の指標となる細胞株)の増殖の用量依存的な刺激作用によって確認されました。

法的情報

HumanKine is a registered trademark of Proteintech Group, Inc. and Humanzyme, Inc

安全性情報

• 保管分類コード: 11 - Combustible Solids
• WGK: WGK 3
• 引火点(°F): Not applicable
• 引火点(℃): Not applicable