H2779

HistoChoice^®Clearing Agent

alternative to toluene and xylene

• 別名: dewaxing mixture for paraffin tissue sections
• UNSPSCコード: 12171500
• NACRES: NA.47

特性

• 品質水準: 100
• 形状: liquid
• 環境により配慮した代替製品の特徴: Designing Safer Chemicals; Learn more about the Principles of Green Chemistry.
• sustainability: Greener Alternative Product
• 色: colorless
• 密度: 0.760-0.820 g/mL
• アプリケーション: hematology; histology
• 環境により配慮した代替製品カテゴリ: , Aligned
• 保管温度: room temp

詳細

詳細

HistoChoice^® is a patented, complex mixture of agents that allow tissues to retain their structure, antigenic sites, and nucleic acid sites. It is a non-toxic, non-cross-linking fixative formulated to replace formaldehyde-based fixation. This formulation in non-citrus, contains no mercury, formaldehyde, or glutaraldehyde.

We are committed to bringing you Greener Alternative Products, which adhere to one or more of The 12 Principles of Greener Chemistry. This product has Inherently Safer Chemistry, compared to the standard use of formalin for tissue processing.

アプリケーション

HistoChoice^® Clearing Agent has the following applications:

• It is suitable as an alternative to toluene and xylene for dewaxing paraffin tissue sections. Prepared slides are suitable for antibody probing applications and in situ hybridizations.
• It has been employed in a study to explain the recalcitrance of lignocellulosic plant cell walls to enzymatic degradation.
• It has been used to develop a novel method to improve sensitivity for the localization of miRNA and their target transcripts in plants.
• It has been used to study the correlation of cytoplasmic ADP-ribosylation levels with markers of patient outcome in human cancers.
  

生物化学的／生理学的作用

Fixation with HistoChoice^® works well in immunohistology applications where its non-cross-linking traits are conducive to epitope retrieval and identification by primary antibodies to extracellular matrix components.

特徴および利点

• Non-toxic, non-carcinogenic, and odorless.
• Non-flammable.
• Preserves native antigenic and nucleic acid sites.
• Compatible with many organic mounting media.
• Dissolves wax faster and evaporates slower than xylene.
• Can be used in automated processors.
• Tissues retain their original structure.

法的情報

HistoChoice is a registered trademark of Amresco, Inc.

安全性情報

• ピクトグラム: GHS07
• シグナルワード: Warning
• 危険有害性情報: H315,H319,H335
• 注意書き: P261 - P264 - P271 - P280 - P302 + P352 - P305 + P351 + P338
• 危険有害性の分類: Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3
• ターゲットの組織: Respiratory system
• 保管分類コード: 10 - Combustible liquids
• WGK: WGK 3
• 引火点(°F): 142.0 °F
• 引火点(℃): 61.1 °C
• 個人用保護具 (PPE): Eyeshields, Gloves, type ABEK (EN14387) respirator filter