F3418

モノクロナール抗サイトケラチン, パン−FITC マウス宿主抗体

clone C-11, purified immunoglobulin, buffered aqueous solution

• 別名: モノクロナール抗パンサイトケラチン
• UNSPSCコード: 12352203
• NACRES: NA.41

特性

• 由来生物: mouse
• 品質水準: 200
• 結合体: FITC conjugate
• 抗体製品の状態: purified immunoglobulin
• 抗体製品タイプ: primary antibodies
• クローン: C-11, monoclonal
• 形状: buffered aqueous solution
• 化学種の反応性: bovine, mouse, frog, human, kangaroo rat, rat
• 保管条件: protect from light
• テクニック: direct immunofluorescence: 1:50 using PtK₂ cells; immunohistochemistry (formalin-fixed, paraffin-embedded sections): 1:50 using human placenta; western blot: suitable
• アイソタイプ: IgG1
• 輸送温度: dry ice
• 保管温度: −20°C
• ターゲットの翻訳後修飾: unmodified
• 遺伝子情報: bovine ... Krt1(100301161) ; human ... KRT1(3848) , KRT13(3858) , KRT13(3858) , KRT18(3875) , KRT18(3875) , KRT4(3851) , KRT4(3851) , KRT5(3852) , KRT5(3852) , KRT6A(3868) , KRT6A(3868) , KRT6B(3854) , KRT6B(3854) , KRT8(3856) , KRT8(3856) ; mouse ... Krt1(16678) , Krt10(16661) , Krt10(16661) , Krt13(16663) , Krt13(16663) , Krt18(16668) , Krt18(16668) , Krt4(16682) , Krt4(16682) , Krt5(110308) , Krt5(110308) , Krt6a(16687) , Krt6a(16687) , Krt6b(16688) , Krt6b(16688) , Krt8(16691) , Krt8(16691) ; rat ... Krt1(300250) , Krt1-18(706059) , Krt1-18(706059) , Krt10(450225) , Krt10(450225) , Krt2-5(369017) , Krt2-5(369017) , Krt2-8(25626) , Krt2-8(25626)

詳細

詳細

Cytokeratins are the intermediate filaments of endocrine cells. These proteins belong to the intermediate filament (10 nm) superfamily of cytoskeletal proteins. Cytokeratins are the largest and most complex group of intermediate filaments. The family consists of at least 30 proteins with molecular weights ranging from 40kDa to 68kDa.

免疫原

keratin-enriched preparation from cultured human epidermoid carcinoma cell line A431.

アプリケーション

Applications in which this antibody has been used successfully, and the associated peer-reviewed papers, are given below.
Immunofluorescence (1 paper)
Immunohistochemistry (1 paper)

Monoclonal Anti-Cytokeratin, pan−FITC antibody has been used in immunocytochemistry and has also been used to visualize lung epithelial cells.

生物化学的／生理学的作用

Cytokeratins helps in subtyping several kinds of epithelial differentiation or for narrowing possible sites of origin for metastatic carcinomas. Cytokeratins may play an important role in transhepatic transport and canalicular secretion.

物理的形状

0.01 M PBS溶液(pH 7.4, 1% BSA, 15 mMアジ化ナトリウム含有)。

免責事項

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

安全性情報

• 保管分類コード: 10 - Combustible liquids
• WGK: nwg
• 引火点(°F): Not applicable
• 引火点(℃): Not applicable
• 個人用保護具 (PPE): Eyeshields, Gloves, multi-purpose combination respirator cartridge (US)