おすすめの製品
由来生物
mouse
品質水準
結合体
unconjugated
抗体製品の状態
purified immunoglobulin
抗体製品タイプ
primary antibodies
クローン
C-11, monoclonal
フォーム
buffered aqueous solution
化学種の反応性
mammals
濃度
1 mg/mL
テクニック
flow cytometry: suitable
アイソタイプ
IgG1
輸送温度
wet ice
保管温度
2-8°C
ターゲットの翻訳後修飾
unmodified
遺伝子情報
human ... KRT1(3848)
詳細
Cytokeratins also known as keratins are filament-forming proteins of epithelial cells. In humans, there are 54 cytokeratins. These proteins are divided in to two sub-categories such as acidic type I keratins and basic-to-neutral type II keratins.
The antibody C-11 reacts with Cytokeratin peptides 4, 5, 6, 8, 10, 13, 18. Cytokeratins are a member of intermediate filaments subfamily represented in epithelial tissues.
免疫原
Keratin-enriched preparation from human epidermoid carcinoma cell line A431
アプリケーション
Monoclonal Anti-Cytokeratin (Pan-reactive) antibody produced in mouse has been used in immunocytochemistry.
The reagent is designed for Flow Cytometry analysis. Suggested working dilution for Flow Cytometry is 0.5 μg/mL of sample. Indicated dilution is recommended starting point for use of this product. Working concentrations should be determined by the investigator.
生物化学的／生理学的作用
Cytokeratins play an essential role in normal tissue structure and function. It also facilitates the maintenance of cell mechanical integrity.
特徴および利点
Evaluate our antibodies with complete peace of mind. If the antibody does not perform in your application, we will issue a full credit or replacement antibody. Learn more.
物理的形状
PBS（pH 7.4、15 mM アジ化ナトリウム含有）
免責事項
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
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保管分類コード
10 - Combustible liquids
引火点(°F)
Not applicable
引火点(℃)
Not applicable
適用法令
試験研究用途を考慮した関連法令を主に挙げております。化学物質以外については、一部の情報のみ提供しています。 製品を安全かつ合法的に使用することは、使用者の義務です。最新情報により修正される場合があります。WEBの反映には時間を要することがあるため、適宜SDSをご参照ください。
Jan Code
SAB4700666-100UG:
Cytokeratin expression, fibrillar organization, and subtle function in liver cells
Marceau N and Loranger A
Biochemistry and Cell Biology = Biochimie Et Biologie Cellulaire, 73, 619-625 (1995)
Evaluation of a simple method for storage of blood samples that enables isolation of circulating tumor cells 96 h after sample collection
Apostolou P
Journal of biological research (Thessalonike?, Greece) (2017)
New consensus nomenclature for mammalian keratins
Schweizer J
The Journal of Cell Biology, 174, 169-174 (2006)
Panagiotis Apostolou et al.
Journal of biological research (Thessalonike, Greece), 24, 11-11 (2017-10-05)
Minimizing the effects of transportation on the properties of biological material is a major challenge for the scientific community. The viability of cells is important in cases where their study is urgent for evaluation of treatment response or for the
Martine Broekema et al.
Kidney international, 68(6), 2572-2581 (2005-12-01)
Ischemia/reperfusion (I/R) injury is a major cause of acute renal failure (ARF). ARF is reversible, due to an innate regenerative process, which is thought to depend partly on bone marrow-derived progenitor cells. The significance of these cells in the repair
ライフサイエンス、有機合成、材料科学、クロマトグラフィー、分析など、あらゆる分野の研究に経験のあるメンバーがおります。.
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