C8395

セフラジン

≥90.0% (Cephradine, HPLC)

• 別名: セフラジン
• 実験式（ヒル表記法）: C₁₆H₁₉N₃O₄S
• CAS番号: 38821-53-3
• 分子量: 349.40
• MDL番号: MFCD00865048
• UNSPSCコード: 51282517
• PubChem Substance ID: 24278342
• NACRES: NA.85

特性

• アッセイ: ≥90.0% (Cephradine, HPLC)
• フォーム: powder
• 溶解性: ethanol: practically insoluble 96%; hexane: practically insoluble; water: slightly soluble
• 抗生物質活性スペクトル: Gram-negative bacteria; Gram-positive bacteria
• 作用機序: cell wall synthesis | interferes
• 保管温度: 2-8°C
• SMILES記法: [H][C@]12SCC(C)=C(N1C(=O)[C@H]2NC(=O)[C@H](N)C3=CCC=CC3)C(O)=O
• InChI: 1S/C16H19N3O4S/c1-8-7-24-15-11(14(21)19(15)12(8)16(22)23)18-13(20)10(17)9-5-3-2-4-6-9/h2-3,6,10-11,15H,4-5,7,17H2,1H3,(H,18,20)(H,22,23)/t10-,11-,15-/m1/s1
• InChI Key: RDLPVSKMFDYCOR-UEKVPHQBSA-N

詳細

詳細

Chemical structure: ß-lactam

アプリケーション

Cefradin was used to study the effect of expression, binding, and inhibition of PBP3 and other penicillin-binding proteins (PBPs) on bacterial cell wall mucopeptide synthesis.

生物化学的／生理学的作用

Cefradin is a semi-synthetic cephalosporin that inhibits the last stage of bacterial cell wall synthesis by binding to certain penicillin-binding proteins (PBPs), such as PBP3, which results in cell lysis. Cell lysis is mediated by bacterial cell wall autolytic enzymes. It is effective against Gram-positive and Gram-negative bacteria. Cefradin may also interfere with autolysin inhibitors.

その他情報

Keep container tightly closed in a dry and well-ventilated place.

安全性情報

• ピクトグラム: GHS08,GHS07
• シグナルワード: Danger
• 危険有害性情報: H315,H317,H319,H334,H335
• 注意書き: P261 - P264 - P271 - P280 - P302 + P352 - P305 + P351 + P338
• 危険有害性の分類: Eye Irrit. 2 - Resp. Sens. 1 - Skin Irrit. 2 - Skin Sens. 1 - STOT SE 3
• ターゲットの組織: Respiratory system
• 保管分類コード: 11 - Combustible Solids
• WGK: WGK 2
• 引火点(°F): Not applicable
• 引火点(℃): Not applicable