B7510

ビューベリシン

≥97% (HPLC), suitable for HPLC

• 別名: シクロ(D-α-ヒドロキシイソバレリル-L-N-メチル-Phe)₃
• 実験式（ヒル表記法）: C₄₅H₅₇N₃O₉
• CAS番号: 26048-05-5
• 分子量: 783.95
• MDL番号: MFCD00056846
• UNSPSCコード: 12352209
• PubChem Substance ID: 24891996
• NACRES: NA.26

特性

• product name: ビューベリシン, ≥97% (HPLC)
• 品質水準: 200
• アッセイ: ≥97% (HPLC)
• 形状: powder or crystals
• テクニック: HPLC: suitable
• 色: white to off-white
• 保管温度: 2-8°C
• SMILES記法: CC(C)C1OC(=O)C(Cc2ccccc2)N(C)C(=O)C(OC(=O)C(Cc3ccccc3)N(C)C(=O)C(OC(=O)C(Cc4ccccc4)N(C)C1=O)C(C)C)C(C)C
• InChI: 1S/C45H57N3O9/c1-28(2)37-40(49)46(7)35(26-32-21-15-11-16-22-32)44(53)56-39(30(5)6)42(51)48(9)36(27-33-23-17-12-18-24-33)45(54)57-38(29(3)4)41(50)47(8)34(43(52)55-37)25-31-19-13-10-14-20-31/h10-24,28-30,34-39H,25-27H2,1-9H3
• InChI Key: GYSCAQFHASJXRS-UHFFFAOYSA-N

詳細

詳細

Beauvericin is a cyclohexadepsipeptide from the fungus Beauveria bassiana that belongs to the enniatin antibiotic family. It comprises three D-hydroxyisovaleryl and N-methylphenylalanyl residues each.

アプリケーション

Beauvericin has been used as an antimicrobial bioactive compound to test its effect on engineered Saccharomyces cerevisiae strains. It has also been used as a mycotoxin standard in the reverse-phase (RP) high-pressure liquid chromatography (HPLC) to quantify mycotoxins produced by Fusarium oxysporum isolates.

生物化学的／生理学的作用

Beauvericin (BEA) is a commercial entomopathogenic mycoinsecticide with antiviral, antibacterial, insecticidal, and cytotoxic properties. It elicits apoptotic and nematicidal activities as well. Beauvericin blocks multidrug efflux and Tor complex 1 (TORC1) kinase. It possesses ionophoric functionality and favors channel formation in patches of ventricular myocytes and synthetic membranes. It is shown to inhibit L-type voltage-dependent Ca²⁺ current in the neuroblastoma cells.

Beauvericin (BEA), a cyclohexadepsipeptide produced by the fungus Beauveria bassiana (Bals.), has antiviral, antibacterial, nematicidal, insecticidal, cytotoxic, and apoptotic activity.

包装

底の開いたガラス瓶内容物は内部に挿入され接着された円錐部に入っています。

安全性情報

• 保管分類コード: 11 - Combustible Solids
• WGK: WGK 3
• 引火点(°F): Not applicable
• 引火点(℃): Not applicable
• 個人用保護具 (PPE): Eyeshields, Gloves, type N95 (US)