A8419

Anti-Human IgG (γ-chain specific)−Peroxidase antibody produced in goat

IgG fraction of antiserum, buffered aqueous solution

• 別名: Goat Anti-Human IgG (gamma-chain specific) HRP
• MDL番号: MFCD00162447
• UNSPSCコード: 12352203
• NACRES: NA.77

特性

• 由来生物: goat
• 結合体: peroxidase conjugate
• 抗体製品の状態: IgG fraction of antiserum
• 抗体製品タイプ: secondary antibodies
• クローン: polyclonal
• 形状: buffered aqueous solution
• テクニック: direct ELISA: 1:40,000; dot blot: 1:100,000 (chemiluminescent); immunohistochemistry (formalin-fixed, paraffin-embedded sections): 1:100
• 輸送温度: dry ice
• 保管温度: −20°C
• ターゲットの翻訳後修飾: unmodified

詳細

詳細

Human IgGs are glycoprotein antibodies that contain two equivalent light chains and a pair of identical heavy chains. IgGs have four distinct isoforms, ranging from IgG1 to IgG4. These antibodies regulate immunological responses to allergy and pathogenic infections. IgGs have also been implicated in complement fixation and autoimmune disorders . The specificity of Anti-Human IgG (γ-chain specific)-Peroxidase antibody is determined by immunoelectrophoresis and Ouchterlony Double Diffusion techniques. This antibody is specific for for human IgG when tested against purified human IgA, IgG, IgM, Bence Jones κ and Bence Jones lambda myeloma proteins.

Immunoglobulin G (IgG) belongs to the immunoglobulin family and is a widely expressed serum antibody. IgG is usually found as a monomer. IgG antibody subtype is the most abundant of serum immunoglobulins of the immune system. About 70 % of the total immunoglobulin consists of IgG.

特異性

This antibody is specific for for human IgG when tested against purified human IgA, IgG, IgM, Bence Jones κ and Bence Jones lambda myeloma proteins.

免疫原

Human IgG

アプリケーション

Anti-Human IgG (γ-chain specific) Peroxidase antibody produced in goat has been used in enzyme-linked immunosorbent assay (ELISA) and western blot.

Applications in which this antibody has been used successfully, and the associated peer-reviewed papers, are given below.
Western Blotting (1 paper)

IgM concentration in sera from patients with chronic CA syndrome was determined by ELISA using HRP-conjugated goat anti-human (mu chain specific) as the secondary antibody.

生物化学的／生理学的作用

Immunoglobulin G (IgG) mainly participates in hypersensitivity type II and type III.

物理的形状

Solution in 0.01 M phosphate buffered saline pH 7.4, containing 0.05% MIT

調製ノート

Avrameas, S., et al., Scand. J. Immunol., 8, Suppl. 7, 7 (1978)に記載の2段階グルタルアルデヒド法により作製しています。

免責事項

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

安全性情報

• ピクトグラム: GHS08
• シグナルワード: Danger
• 危険有害性情報: H317,H334
• 注意書き: P261 - P272 - P280 - P284 - P302 + P352 - P333 + P313
• 危険有害性の分類: Resp. Sens. 1 - Skin Sens. 1
• 保管分類コード: 12 - Non Combustible Liquids
• WGK: WGK 2
• 引火点(°F): Not applicable
• 引火点(℃): Not applicable