938963

Potassium tert-butoxide ChemBeads

• 別名: Potassium tert-butylate, Potassium t-butoxide
• 実験式（ヒル表記法）: KOC₄H₉
• CAS番号: 865-47-4
• 分子量: 112.21
• MDL番号: MFCD00012162
• UNSPSCコード: 12352100

特性

• 詳細: Reagent Type-Organic Salt
• 品質水準: 100
• 形状: solid
• 組成: wt% loading of base, 14-16 wt. %
• 反応適合性: core: potassium
• SMILES記法: [K+].CC(C)(C)[O-]
• InChI: 1S/C4H9O.K/c1-4(2,3)5;/h1-3H3;/q-1;+1
• InChI Key: LPNYRYFBWFDTMA-UHFFFAOYSA-N

詳細

詳細

Potassium tert-butoxide is a strong alkoxide base, it can deprotonate carbon and other Brφnsted acids. It is a relatively poor nucleophile.

アプリケーション

Potassium tert-butoxide has been used as a strong base in the enantioselective synthesis of amines by transfer hydrogenation of N-(tertbutylsulfinyl)imines. It can also be used: To synthesize aliphatic and aromatic amides from corresponding esters and amines. As a base in the intramolecular cyclization of aryl ethers, amines, and amides. As a catalyst to prepare styrene derivatives from aryl halides and alkenes by Mizoroki-Heck reaction.
For general uses, product is also available in powdered form (156671)

特徴および利点

ChemBeads are chemical coated glass beads. ChemBeads offer improved flowability and chemical uniformity perfect for automated solid dispensing and high-throughput experimentation. The method of creating ChemBeads uses no other chemicals or surfactants allowing the user to accurately dispense sub-milligram amounts of chemical.

その他情報

High-Throughput Reaction Screening with Nanomoles of Solid Reagents Coated on Glass Beads

Versatile Methods to Dispense Sub-Milligram Quantities of Solids using Chemical Coated Beads for High-Throughput Experimentation

ChemBead Enabled High-Throughput Cross-Electrophile Coupling Reveals a New Complementary Ligand

安全性情報

• ピクトグラム: GHS02,GHS05
• シグナルワード: Danger
• 危険有害性情報: H228,H252,H314
• 注意書き: P210 - P235 - P260 - P280 - P303 + P361 + P353 - P305 + P351 + P338
• 危険有害性の分類: Eye Dam. 1 - Flam. Sol. 1 - Self-heat. 2 - Skin Corr. 1A
• 補足的ハザード: EUH014
• 保管分類コード: 4.2 - Pyrophoric and self-heating hazardous materials
• WGK: WGK 3