MATRESIQUIM0D

Resiquimod Non-Endotoxin Pyrogen (NEP) Control

for use with PyroMAT^®

• 別名: Imidazoquinolinon
• UNSPSCコード: 41116129
• NACRES: NA.74

特性

• 認証: EP; JP 4.06; USP
• 品質水準: 400
• 形状: lyophilized
• アプリケーション: pharmaceutical; pyrogen testing
• 適合性: for use with PyroMAT^®; pyrogenic bacteria
• 輸送温度: ambient
• 保管温度: −20°C

詳細

詳細

Resiquimod is a non-endotoxin pyrogen which will serve as a positive control during pyrogen testing with PyroMAT^® system.Non- Endotoxin Pyrogen (NEP) Control Resiquimod is an imidazoquinolinone compound possessing a potent anti-viral activity, supplied in a lyophilized form. It is designed to mimic the NEPs of viral origin. Resiquimod Non- Endotoxin Pyrogen (NEP) Control activates TLR7/TLR8 receptor of monocytes and is used as a positive control for PyroMAT^® system. The response to pyrogenic substances is determined by measuring the Interleukin-6 (IL-6) produced by the monocytes using ELISA microplate.

アプリケーション

Resiquimod Non- Endotoxin Pyrogen (NEP) Control can be used as a positive control with the PyroMAT^® System. It is to be used for Product Specific Validation (PSV) and routine testing to show that the system can detect non-endotoxin pyrogen contaminants in pharmaceutical products.

法的情報

PYROMAT is a registered trademark of Merck KGaA, Darmstadt, Germany

安全性情報

• 保管分類コード: 11 - Combustible Solids
• WGK: WGK 3
• 引火点(°F): Not applicable
• 引火点(℃): Not applicable