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由来生物
goat
品質水準
結合体
peroxidase conjugate
抗体製品の状態
affinity purified immunoglobulin
抗体製品タイプ
secondary antibodies
クローン
polyclonal
形状
lyophilized
化学種の反応性
human
メーカー／製品名
Chemicon®
濃度
1.0 mg/mL
テクニック
ELISA: suitable
western blot: suitable
アイソタイプ
IgG
輸送温度
wet ice
保管温度
2-8°C
ターゲットの翻訳後修飾
unmodified
詳細
Immunoglobulin G (IgG) is the main type of glycoprotein antibody found in human serum, secreted by the B cells. It is found in blood and comprises four polypeptide chains, made of two identical 50 kDa γ heavy (H) chains and two identical 25 kDa κ or λ light (L) chains. These chains are inter-linked by di-sulfide bonds. IgG exists in four isotypes IgG1, IgG2, IgG3 and IgG4. IgG has the longest serum half-life compared to other immunoglobulins.
特異性
Specific for human IgG gamma chain. The cross-reactivities of anti-human IgG (gamma) antibody are tested in an ELISA. Minimal cross-reactivity to light chains.
The reagent is an affinity purified antibody from goat. The purified antibody is conjugated to horseradish peroxidase (HRP) and stabilized in buffer.
The reagent is an affinity purified antibody from goat. The purified antibody is conjugated to horseradish peroxidase (HRP) and stabilized in buffer.
アプリケーション
ELISA: 1:3,000
Immunohistochemistry: 1:200-1:500 (1-4)
Immunocytochemistry: 1:200-1:500 (1-4)
Western Blot, chromogenic: 1:200-1-500
Western Blot, chemiluminescent: 1:2,000-1:5,000
Optimal working dilutions must be determined by the end user.
Immunohistochemistry: 1:200-1:500 (1-4)
Immunocytochemistry: 1:200-1:500 (1-4)
Western Blot, chromogenic: 1:200-1-500
Western Blot, chemiluminescent: 1:2,000-1:5,000
Optimal working dilutions must be determined by the end user.
生物化学的／生理学的作用
Immunoglobulin G (IgG) initiates the classical pathway of the complement system. It neutralizes virus particles and toxins. IgG plays a vital role in antibody-dependent cell-mediated cytotoxicity (ADCC) and might be associated with allergy. Maternal IgG is transferred to the fetus through the placenta that is crucial for the immune defense of the neonate against infections. Digestion of IgG by papain results in the production of fragment antigen-binding (Fab). Pepsin digestion of IgG leads to the generation of fragment crystallizable (Fc). Levels of IgG in severe acute respiratory syndrome coronavirus (SARS-CoV)-2 infected patients can be used as a potential tool to evaluate the severity and prognosis of coronavirus disease 2019 (COVID-19).
物理的形状
ImmunoAffinity Purified
保管および安定性
The undiluted antibody is stable at 2-8°C for 12 months. Do not store in a diluted format. DO NOT FREEZE.
法的情報
CHEMICON is a registered trademark of Merck KGaA, Darmstadt, Germany
免責事項
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
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保管分類コード
13 - Non Combustible Solids
WGK
WGK 3
引火点(°F)
Not applicable
引火点(℃)
Not applicable
適用法令
試験研究用途を考慮した関連法令を主に挙げております。化学物質以外については、一部の情報のみ提供しています。 製品を安全かつ合法的に使用することは、使用者の義務です。最新情報により修正される場合があります。WEBの反映には時間を要することがあるため、適宜SDSをご参照ください。
Jan Code
AP309P:
試験成績書（COA）
製品のロット番号・バッチ番号を入力して、試験成績書（COA） を検索できます。ロット番号・バッチ番号は、製品ラベルに「Lot」または「Batch」に続いて記載されています。
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