516705

o-Phenanthroline

A metal chelating agent that prevents the induction of chromosomal aberrations in streptozotocin-treated cells.

• 別名: o-Phenanthroline, 1,10-Phenanthroline Monohydrate
• 実験式（ヒル表記法）: C₁₂H₈N₂ · xH₂O
• CAS番号: 5144-89-8
• 分子量: 180.21 (anhydrous basis)
• MDL番号: MFCD00149973
• UNSPSCコード: 51111800
• NACRES: NA.77

特性

• 品質水準: 100
• アッセイ: ≥99% (titration)
• 形状: solid
• メーカー／製品名: Calbiochem^®
• 保管条件: OK to freeze; protect from light
• 色: white to cream
• 溶解性: DMSO: 100 mg/mL; ethanol: 25 mg/mL; water: 3 mg/mL
• 輸送温度: ambient
• 保管温度: 10-30°C
• InChI: 1S/C12H8N2.H2O/c1-3-9-5-6-10-4-2-8-14-12(10)11(9)13-7-1;/h1-8H;1H2
• InChI Key: PPQJCISYYXZCAE-UHFFFAOYSA-N

詳細

詳細

A metal chelating agent that prevents the induction of chromosomal aberrations in streptozotocin-treated cells. Acts as a general matrix metalloproteinase inhibitor. Forms a red chelate with Fe²⁺ that absorbs maximally at 510 nm. Can be used as a photometric reagent for iron.

A metal chelating agent that prevents the induction of chromosomal aberrations in streptozotocin-treated cells. Acts as a metalloprotease inhibitor. Inhibits glioma invasion in vitro.

生物化学的／生理学的作用

Cell permeable: no

Primary Target
Metalloprotease inhibitor

Product does not compete with ATP.

Reversible: no

包装

Packaged under inert gas

警告

Toxicity: Toxic (F)

その他情報

Due to the nature of the Hazardous Materials in this shipment, additional shipping charges may be applied to your order. Certain sizes may be exempt from the additional hazardous materials shipping charges. Please contact your local sales office for more information regarding these charges.

Stix, B., et al. 2001. Am. J. Pathol.159, 561.
Bolzan, A.D., et al. 2000. Mutat. Res.447, 221.
Wang, Y., et al. 1999. J. Biol. Chem.274, 33043.
Harayama, T., et al. 1999. Jpn. J. Can. Res.90, 942.
Krane, S.M., et al. 1996. J. Biol. Chem.271, 28509.
Uhm, J.H., et al. 1996. Clin. Exp. Metastasis14, 421.

法的情報

CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany

安全性情報

• ピクトグラム: GHS06,GHS09
• シグナルワード: Danger
• 危険有害性情報: H301,H410
• 注意書き: P264 - P273 - P301 + P310 - P391 - P405 - P501
• 危険有害性の分類: Acute Tox. 3 Oral - Aquatic Acute 1 - Aquatic Chronic 1
• 保管分類コード: 6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects
• WGK: WGK 3
• 引火点(°F): Not applicable
• 引火点(℃): Not applicable