P-004

Phenobarbital-D₅ (side chain) solution

(deuterium label on side chain), 100 μg/mL in methanol, ampule of 1 mL, certified reference material, Cerilliant^®

• 実験式（ヒル表記法）: C₁₂D₅H₇N₂O₃
• CAS番号: 73738-05-3
• 分子量: 237.27
• EC Number: 200-659-6
• MDL番号: MFCD00145091
• UNSPSCコード: 41116107
• PubChem Substance ID: 329819991
• NACRES: NA.24

特性

• グレード: certified reference material
• 形状: liquid
• 特徴: Snap-N-Spike^®/Snap-N-Shoot^®
• 包装: ampule of 1 mL
• メーカー／製品名: Cerilliant^®
• drug control: Narcotic Licence Schedule B (Switzerland); psicótropo (Spain); Decreto Lei 15/93: Tabela IV (Portugal)
• 濃度: 100 μg/mL in methanol
• テクニック: gas chromatography (GC): suitable; liquid chromatography (LC): suitable
• アプリケーション: forensics and toxicology
• フォーマット: single component solution
• 保管温度: 2-8°C
• SMILES記法: [2H]C([2H])([2H])C([2H])([2H])C1(C(=O)NC(=O)NC1=O)c2ccccc2
• InChI: 1S/C12H12N2O3/c1-2-12(8-6-4-3-5-7-8)9(15)13-11(17)14-10(12)16/h3-7H,2H2,1H3,(H2,13,14,15,16,17)/i1D3,2D2
• InChI Key: DDBREPKUVSBGFI-ZBJDZAJPSA-N

詳細

詳細

An internal standard suitable for quantitation of phenobarbital levels in GC/MS or LC/MS applications for clinical toxicology, urine drug testing, or forensic analysis. Phenobarbital is a barbiturate used to treat all epileptic seizure types except for absence seizures. Phenobarbital is the oldest and most widely used anticonvulsant.

アプリケーション

• Internal standard application strategies in mass spectrometry imaging by desorption electrospray ionization mass spectrometry: This study utilizes Phenobarbital-D5 as a stable isotope-labeled internal standard in mass spectrometry imaging, highlighting its critical role in enhancing the accuracy and reliability of quantitative measurements in complex biological samples, particularly in pharmacokinetic studies (Perez and Ifa, 2021).
• Determination of barbiturates in hair samples by using a validated UHPLC-HRMS method: This research employs Phenobarbital-D5 to calibrate and validate an ultra-high performance liquid chromatography-high resolution mass spectrometry (UHPLC-HRMS) method, aimed at investigating drug-facilitated crimes. The study demonstrates the utility of deuterated standards like Phenobarbital-D5 in forensic toxicology to ensure accurate detection and quantification of drugs in forensic samples (Wen et al., 2022).

法的情報

CERILLIANT is a registered trademark of Merck KGaA, Darmstadt, Germany

Snap-N-Shoot is a registered trademark of Cerilliant Corporation

Snap-N-Spike is a registered trademark of Merck KGaA, Darmstadt, Germany

安全性情報

• ピクトグラム: GHS02,GHS06,GHS08
• シグナルワード: Danger
• 危険有害性情報: H225,H301 + H311 + H331,H370
• 注意書き: P210 - P280 - P301 + P310 + P330 - P302 + P352 + P312 - P304 + P340 + P311
• 危険有害性の分類: Acute Tox. 3 Dermal - Acute Tox. 3 Inhalation - Acute Tox. 3 Oral - Flam. Liq. 2 - STOT SE 1
• ターゲットの組織: Eyes
• 保管分類コード: 3 - Flammable liquids
• WGK: WGK 1
• 引火点(°F): 49.5 °F - closed cup
• 引火点(℃): 9.7 °C - closed cup