363839

N-(tert-Butoxycarbonyl)-p-toluenesulfonamide

• 化学式: CH₃C₆H₄SO₂NHCO₂C(CH₃)₃
• CAS番号: 18303-04-3
• 分子量: 271.33
• MDL番号: MFCD00134267
• UNSPSCコード: 12352100
• PubChem Substance ID: 24862365
• NACRES: NA.22

特性

• mp: 121-123 °C (lit.)
• 溶解性: chloroform: soluble 25 mg/mL, clear, colorless
• 官能基: amine
• SMILES記法: Cc1ccc(cc1)S(=O)(=O)NC(=O)OC(C)(C)C
• InChI: 1S/C12H17NO4S/c1-9-5-7-10(8-6-9)18(15,16)13-11(14)17-12(2,3)4/h5-8H,1-4H3,(H,13,14)
• InChI Key: DUTLOVSBVBGNDM-UHFFFAOYSA-N

詳細

詳細

N-(tert-Butoxycarbonyl)-p-toluenesulfonamide is a N-substituted sulphonamide and its reaction with N-trityl L-serine esters under Mitsunobu reaction conditions is reported. It can be directly coupled with primary, secondary and allylic alcohols under Mitsunobu conditions to afford various sulfonyl-protected amines.

アプリケーション

N-(tert-Butoxycarbonyl)-p-toluenesulfonamide may be used in the preparation of enyne amide, precursor for Pauson-Khand reaction.

安全性情報

• 保管分類コード: 10 - Combustible liquids
• WGK: WGK 3
• 引火点(°F): Not applicable
• 引火点(℃): Not applicable