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品質水準
アッセイ
98%
bp
227-228 °C (lit.)
mp
42-44 °C (lit.)
官能基
chloro
fluoro
SMILES記法
Nc1ccc(F)c(Cl)c1
InChI
1S/C6H5ClFN/c7-5-3-4(9)1-2-6(5)8/h1-3H,9H2
InChI Key
YSEMCVGMNUUNRK-UHFFFAOYSA-N
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詳細
The exposure of workers to 3-chloro-4-fluoroaniline (CFA) was monitored by an HPLC method.
シグナルワード
Danger
危険有害性情報
危険有害性の分類
Acute Tox. 3 Dermal - Acute Tox. 3 Inhalation - Acute Tox. 3 Oral - STOT RE 2
保管分類コード
6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects
WGK
WGK 2
引火点(°F)
230.0 °F - closed cup
引火点(℃)
110 °C - closed cup
個人用保護具 (PPE)
Eyeshields, Faceshields, Gloves, type P2 (EN 143) respirator cartridges
適用法令
試験研究用途を考慮した関連法令を主に挙げております。化学物質以外については、一部の情報のみ提供しています。 製品を安全かつ合法的に使用することは、使用者の義務です。最新情報により修正される場合があります。WEBの反映には時間を要することがあるため、適宜SDSをご参照ください。
Jan Code
228583-BULK:
228583-VAR:
228583-25G:
228583-100G:
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C V Eadsforth et al.
Journal of analytical toxicology, 12(6), 330-333 (1988-11-01)
An HPLC method for monitoring exposure of workers to 3-chloro-4-fluoroaniline (CFA) is described. It is based on the detection of a major urinary metabolite, 2-amino-4-chloro-5-fluorophenyl sulphate, and is superior to the previously adopted GC method. The limit of detection for
C J Duckett et al.
Xenobiotica; the fate of foreign compounds in biological systems, 36(1), 59-77 (2006-03-02)
The metabolic fate of 3-chloro-4-fluoroaniline was investigated in rat following intraperitoneal (i.p.) administration at 5 and 50 mg kg(-1) using a combination of HPLC-MS, HPLC-MS/MS, (19)F-NMR spectroscopy, HPLC-NMR spectroscopy and high-pressure liquid chromatography-inductively coupled plasma mass spectrometry (HPLC-ICPMS) with (35)Cl
M K Baldwin et al.
Xenobiotica; the fate of foreign compounds in biological systems, 10(2), 135-144 (1980-02-01)
1. 3-Chloro-4-fluorol[14C]aniline, orally administered to a female dog (0.135 mg/kg), was eliminated in the urine as 2-amino-4-chloro-5-fluorophenyl sulphate (83% in 48 h). 2. When 3-chloro-4-fluoro[14C]aniline was administered orally to male rats (ca 2.3 mg/kg), the 0-24 h urine contained 2-amino-4-chloro-5-fluorophenyl
P J Boogaard et al.
Environmental health perspectives, 102 Suppl 6, 23-25 (1994-10-01)
In two studies, involving 75 and 72 workers, potential exposure to 3-chloro-4-fluoroaniline (CFA) was biologically monitored by determination of its main urinary metabolite 2-amino-4-chloro-5-fluorophenol sulfate (CFA-S). As this method only allows the detection of recent exposure, analysis of CFA adducts
Vasili Travkin et al.
FEMS microbiology letters, 209(2), 307-312 (2002-05-15)
In this paper we report the isolation and characterization of an anaerobic enrichment culture as well as of a Rhodococcus sp. strain 2 capable of degrading 3,4-dihaloanilines under nitrate reducing conditions. Using mass spectrometry several of the intermediates formed in
プロトコル
GC Analysis of Anilines on Equity®-5
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