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Merck

NOS1

nitric oxide synthase 1 (neuronal)

別名:
IHPS1, N-NOS, NC-NOS, NOS, bNOS, nNOS
Species:
UniProtKB ID:
遺伝子ID:
  • Human(4842) Summary: The protein encoded by this gene belongs to the family of nitric oxide synthases, which synthesize nitric oxide from L-arginine. Nitric oxide is a reactive free radical, which acts as a biologic mediator in several processes, including neurotransmission, and antimicrobial and antitumoral activities. In the brain and peripheral nervous system, nitric oxide displays many properties of a neurotransmitter, and has been implicated in neurotoxicity associated with stroke and neurodegenerative diseases, neural regulation of smooth muscle, including peristalsis, and penile erection. This protein is ubiquitously expressed, with high level of expression in skeletal muscle. Multiple transcript variants that differ in the 5' UTR have been described for this gene but the full-length nature of these transcripts is not known. Additionally, alternatively spliced transcript variants encoding different isoforms (some testis-specific) have been found for this gene.[provided by RefSeq, Feb 2011]
  • Mouse(18125) nitric oxide synthase 1, neuronal
  • Rat(24598) nitric oxide synthase 1, neuronal
  • Zebrafish(60658) nitric oxide synthase 1 (neuronal)
  • domestic cat(101100342) nitric oxide synthase 1 (neuronal)
  • cow(536132) nitric oxide synthase 1 (neuronal)
  • Horse(100051079) nitric oxide synthase 1 (neuronal)
  • dog(477498) nitric oxide synthase 1 (neuronal)
  • chicken(427721) nitric oxide synthase 1 (neuronal)
  • naked mole-rat(101711993) nitric oxide synthase 1 (neuronal)
  • Domestic Rabbit(100009243) nitric oxide synthase 1 (neuronal)
  • domestic guinea pig(100729682) nitric oxide synthase 1 (neuronal)

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Small Molecule - Antagonist

製品番号
詳細
Species
(−)-サリドマイド, >98%, solid,
Species
human, mouse, rat
(+)-サリドマイド, ≥98% (HPLC), powder,
Species
human, mouse, rat
アンモニウムピロリジンジチオカルバメート, ~99%,
Species
human
メラトニン, powder, ≥98% (TLC),
Species
human
(±)-サリドマイド, ≥98%, powder,
Species
human, mouse, rat

Antibodies

製品番号
詳細
交差性
アプリケーション
抗ニトロチロシン抗体, Upstate®, from rabbit,
交差性
all
アプリケーション
immunocytochemistry
immunohistochemistry

immunoprecipitation (IP)

western blot
抗ニトロチロシン抗体, Chemicon®, from rabbit,
交差性
all, human, mouse
アプリケーション
immunohistochemistry
western blot
抗ニトロチロシン ウサギ宿主抗体, affinity isolated antibody, buffered aqueous solution,
交差性
wide range
アプリケーション
ELISA
immunofluorescence

immunohistochemistry

microarray

western blot
Anti-Nitric Oxide Synthase I Antibody, serum, Chemicon®,
交差性
human, monkey, mouse, rat, sheep
アプリケーション
immunohistochemistry
western blot
Anti-Nitrotyrosine Antibody, clone 1A6, Alexa Fluor 555 conjugate, clone 1A6, Upstate®, from mouse,
交差性
vertebrates
アプリケーション
flow cytometry
western blot

Small Molecule - Inhibitor

製品番号
詳細
Species
スペルミジン 三塩酸塩, ≥98% (TLC),
Species
human
4-ニトロカテコール, ≥96.0%,
Species
rat
5-メチル-2-ニトロアニリン, 95%,
Species
rat
2,6-ジ-tert-ブチル-4-メチルフェノール, ≥99.0% (GC), powder,
Species
rat, human
L-アルギニン, from non-animal source, meets EP, USP testing specifications, suitable for cell culture, 98.5-101.0%,
Species
rat, human

Small Molecule - Precursor

製品番号
詳細
Species
L-アルギニン, from non-animal source, meets EP, USP testing specifications, suitable for cell culture, 98.5-101.0%,
Species
rat, human
L-アルギニン, ,
Species
rat, human
L-アルギニン, 99%, FCC, FG,
Species
rat, human
L-アルギニン, reagent grade, ≥98%,
Species
rat, human
L-アルギニン, BioUltra, ≥99.5% (NT),
Species
rat, human

esiRNA

製品番号
詳細
Species
MISSION® esiRNA, targeting mouse Nos1,
Species
mouse