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Key Documents

P6617

Sigma-Aldrich

Pristanic acid

≥97% (GC), ethanol solution

Sinonimo/i:

2,6,10,14-Tetramethylpentadecanoic acid

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About This Item

Formula empirica (notazione di Hill):
C19H38O2
Numero CAS:
Peso molecolare:
298.50
Numero CE:
Numero MDL:
Codice UNSPSC:
12352106
ID PubChem:
NACRES:
NA.77

product name

Pristanic acid solution, mixture of isomers, ethanol solution, ≥97% (GC)

Livello qualitativo

Saggio

≥97% (GC)

Forma fisica

ethanol solution

Temperatura di conservazione

−20°C

Stringa SMILE

CC(C)CCCC(C)CCCC(C)CCCC(C)C(O)=O

InChI

1S/C19H38O2/c1-15(2)9-6-10-16(3)11-7-12-17(4)13-8-14-18(5)19(20)21/h15-18H,6-14H2,1-5H3,(H,20,21)
PAHGJZDQXIOYTH-UHFFFAOYSA-N

Azioni biochim/fisiol

Oxidation product of fatty acids in the diet, particularly phytanic acid. Phytanic acid is oxidized by alpha oxidation yielding pristanic acid, which is subsequently degraded by peroxisomal beta oxidation. Several inborn errors of metabolism with one or more deficiencies in the phytanic acid and pristanic acid breakdown have been described.

Pittogrammi

FlameExclamation mark

Avvertenze

Danger

Indicazioni di pericolo

Classi di pericolo

Eye Irrit. 2 - Flam. Liq. 2

Codice della classe di stoccaggio

3 - Flammable liquids

Classe di pericolosità dell'acqua (WGK)

WGK 2

Punto d’infiammabilità (°F)

55.4 °F

Punto d’infiammabilità (°C)

13 °C

Dispositivi di protezione individuale

Eyeshields, Faceshields, Gloves, type ABEK (EN14387) respirator filter


Certificati d'analisi (COA)

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Sigma-Aldrich

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Sigma-Aldrich

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Behenic acid analytical standard

Supelco

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Supelco

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Sigma-Aldrich

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James A Mobley et al.
Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology, 12(8), 775-783 (2003-08-15)
An enzyme previously identified as alpha-methylacyl-CoA racemase (AMACR) is overexpressed in high-grade prostatic intraepithelial neoplasia and in a majority (60-100%) of prostate cancers (CaPs) as compared with normal and benign hyperplastic lesions of the prostate, where it is minimally expressed.
Biochemical markers predicting survival in peroxisome biogenesis disorders.
Jeannette Gootjes et al.
Advances in experimental medicine and biology, 544, 67-68 (2004-01-10)
J Gootjes et al.
Neurology, 59(11), 1746-1749 (2002-12-11)
To identify prognostic markers reflecting the extent of peroxisome dysfunction in primary skin fibroblasts from patients with peroxisome biogenesis disorders (PBD). PBD are a genetically heterogeneous group of disorders due to defects in at least 11 distinct genes. Zellweger syndrome
Phytanic and pristanic acid are naturally occuring ligands.
Anna W M Zomer et al.
Advances in experimental medicine and biology, 544, 247-254 (2004-01-10)
R J Wanders et al.
European journal of pediatrics, 153(7 Suppl 1), S44-S48 (1994-01-01)
Peroxisomal disorders represent a recently recognized group of inherited diseases in man, now comprising 14 different disorders. If discussion is restricted to those peroxisomal disorders in which there is neurological involvement (thereby excluding hyperoxaluria and acatalasaemia), results over the least

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