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Merck
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Documenti fondamentali

H5659

Sigma-Aldrich

L-istidina

98.5-101.0%, suitable for cell culture, BioXtra, non-animal source

Sinonimo/i:

Acido L-α-amino-β-(4-imidazolil)propionico

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About This Item

Formula empirica (notazione di Hill):
C6H9N3O2 · HCl · H2O
Numero CAS:
Peso molecolare:
209.63
Beilstein:
4168261
Numero MDL:
Codice UNSPSC:
12352209
eCl@ss:
32160406
ID PubChem:
NACRES:
NA.26

Nome del prodotto

L-istidina, from non-animal source, meets EP testing specifications, suitable for cell culture, 98.5-101.0%

Origine biologica

non-animal source

Livello qualitativo

agenzia

meets EP testing specifications

Nome Commerciale

BioXtra

Saggio

98.5-101.0%

Stato

crystalline powder

tecniche

cell culture | mammalian: suitable

Impurezze

endotoxin, tested

Colore

white

Punto di fusione

254 °C (dec.) (lit.)

Solubilità

H2O: 100 mg/mL

Stringa SMILE

O.Cl.N[C@@H](Cc1c[nH]cn1)C(O)=O

InChI

1S/C6H9N3O2.ClH.H2O/c7-5(6(10)11)1-4-2-8-3-9-4;;/h2-3,5H,1,7H2,(H,8,9)(H,10,11);1H;1H2/t5-;;/m0../s1
CMXXUDSWGMGYLZ-XRIGFGBMSA-N

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Applicazioni

L-Histidine monohydrochloride monohydrate has been used in bee cell culture medium.
L-Histidine monohydrochloride, non-animal, is used in cell culture media formulations used in biomanufacturing. The use of non-animal-sourced L-Histidine and other components avoids the risk of contaminating bioproducts with adventitious viruses.

Azioni biochim/fisiol

L-Histidine is involved in the one-carbon unit metabolism. It is associated with protein methylation. L-Histidine is a part of hemoglobin structure and function. L-Histidine is a component of dipeptides with antioxidative property. Histidine serves as a precursor for the formation of histamine, which is associated with allergic responses. Urocanic acid, an immune response modulator in skin is also biosynthesised from histidine.

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Codice della classe di stoccaggio

11 - Combustible Solids

Classe di pericolosità dell'acqua (WGK)

WGK 1

Punto d’infiammabilità (°F)

Not applicable

Punto d’infiammabilità (°C)

Not applicable

Dispositivi di protezione individuale

Eyeshields, Gloves, type N95 (US)


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Medium for development of bee cell cultures (Apis mellifera: Hymenoptera: Apidae).
Hunter WB
In Vitro Cellular & Developmental Biology. Animal, 46(2), 83-86 (2010)
D J Williams et al.
IEE proceedings. Nanobiotechnology, 152(6), 207-210 (2006-01-31)
Tissue engineering and regenerative medicine are interdisciplinary fields that apply principles of engineering and life sciences to develop biological substitutes, typically composed of biological and synthetic components, that restore, maintain or improve tissue function. Many tissue engineering technologies are still
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Biotechnology advances, 30(5), 1140-1157 (2011-10-11)
Insect cells (IC) and particularly lepidopteran cells are an attractive alternative to mammalian cells for biomanufacturing. Insect cell culture, coupled with the lytic expression capacity of baculovirus expression vector systems (BEVS), constitutes a powerful platform, IC-BEVS, for the abundant and
Yoshihiro Kaneko et al.
Journal of bioscience and bioengineering, 109(3), 274-280 (2010-02-18)
Pharmaceutical manufacturing plants can be operated continuously for several months. It is therefore important to use cells with long-term stability for the production of active ingredients. We investigated the reliability and long-term stability of an antibody-producing cell line. A recombinant
Carlota Diaz Sanchez-Bustamante et al.
Biotechnology and bioengineering, 93(1), 169-180 (2005-10-29)
A precise understanding of processes managing heterologous protein production in vitro and in vivo is essential for the manufacture of sophisticated biopharmaceuticals as well as for future gene therapy and tissue engineering initiatives. Capitalizing on the gravity-enforced self-assembly of monodispersed

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