34392
Methyldibromoglutaronitrile
analytical standard
Sinonimo/i:
1,2-Dibromo-2,4-dicyanobutane, 1-Bromo-1-(bromomethyl)-1,3-propanedicarbonitrile, 2-Bromo-2-(bromomethyl)glutaronitrile
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About This Item
Formula empirica (notazione di Hill):
C6H6Br2N2
Numero CAS:
Peso molecolare:
265.93
Numero CE:
Numero MDL:
Codice UNSPSC:
85151701
ID PubChem:
NACRES:
NA.24
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Grado
analytical standard
Livello qualitativo
Durata
limited shelf life, expiry date on the label
tecniche
HPLC: suitable
gas chromatography (GC): suitable
Punto di fusione
51-55 °C
applicazioni
environmental
Formato
neat
Temperatura di conservazione
2-8°C
Stringa SMILE
BrCC(Br)(CCC#N)C#N
InChI
1S/C6H6Br2N2/c7-4-6(8,5-10)2-1-3-9/h1-2,4H2
DHVLDKHFGIVEIP-UHFFFAOYSA-N
Categorie correlate
Descrizione generale
Methyldibromoglutaronitrile (MDBGN) is a bromine-containing preservative and a clinically significant allergen as investigated from animal/human clinical studies.
Methyldibromoglutaronitrile can be generally used as a preservative in the cosmetic industry for many skin care products.
Applicazioni
Methyldibromoglutaronitrile may be used as an analytical reference standard for the quantification of the analyte in cosmetic products using ultra performance liquid chromatography (UPLC) coupled to inductively coupled plasma mass spectrometry (ICP-MS) and gas chromatography followed by mass spectrometry technique.
Refer to the product′s Certificate of Analysis for more information on a suitable instrument technique. Contact Technical Service for further support.
Prodotti consigliati
Find a digital Reference Material for this product available on our online platform ChemisTwin® for NMR. You can use this digital equivalent on ChemisTwin® for your sample identity confirmation and compound quantification (with digital external standard). An NMR spectrum of this substance can be viewed and an online comparison against your sample can be performed with a few mouseclicks. Learn more here and start your free trial.
Avvertenze
Danger
Indicazioni di pericolo
Classi di pericolo
Acute Tox. 4 Oral - Skin Corr. 1B
Codice della classe di stoccaggio
8A - Combustible, corrosive hazardous materials
Classe di pericolosità dell'acqua (WGK)
WGK 2
Punto d’infiammabilità (°F)
Not applicable
Punto d’infiammabilità (°C)
Not applicable
Dispositivi di protezione individuale
Eyeshields, Faceshields, Gloves, type P3 (EN 143) respirator cartridges
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Axel Schnuch et al.
Contact dermatitis, 56(6), 331-337 (2007-06-20)
Although genetic factors probably account for differences in susceptibility to contact allergy, they have not yet been identified, partly due to an insufficient understanding of 'susceptibility'. Regarding polysensitization (PS) as a sign of increased susceptibility, we studied the relationship between
Louise Arup Fischer et al.
Contact dermatitis, 61(4), 201-208 (2009-10-15)
Allergic contact dermatitis is common and can be prevented. The relationship between thresholds for patch tests and the repeated open application test (ROAT) is unclear. It would be desirable if patch test and ROAT data from already sensitized individuals could
Patch testing with methyldibromoglutaronitrile
Geier J, et al.
American Journal of Contact Dermatitis : Official Journal of the American Contact Dermatitis Society, 11, 207-212 (2000)
S Ada et al.
Journal of the European Academy of Dermatology and Venereology : JEADV, 24(10), 1192-1196 (2010-03-20)
Cosmetics are the causative agents in 8-15% of patients suspected of having allergic contact dermatitis. Patch testing with standard series identifies 70-80% of the responsible allergens in all contact dermatitis; however, many important cosmetic-related allergens may be missed by using
Huijun Liu et al.
Bulletin of environmental contamination and toxicology, 92(4), 451-454 (2014-02-20)
The dissipation and residues of bromothalonil in apple and soil under field condition were analyzed by QuEChERS (quick, easy, cheap, effective, rugged and safe) combined with gas chromatography-mass spectrometer method. The recoveries were ranged from 80.8 % to 106 %
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