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Key Documents

1136002

USP

Clindamycin hydrochloride

United States Pharmacopeia (USP) Reference Standard

Sinônimo(s):

Clindamycin hydrochloride monohydrate, (7S)-7-Chloro-7-deoxylincomycin hydrochloride monohydrate

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About This Item

Fórmula empírica (Notação de Hill):
C18H33ClN2O5S · HCl · H2O
Número CAS:
Peso molecular:
479.46
Código UNSPSC:
41116107
NACRES:
NA.24

grau

pharmaceutical primary standard

família API

clindamycin

fabricante/nome comercial

USP

aplicação(ões)

pharmaceutical (small molecule)

formato

neat

temperatura de armazenamento

2-8°C

InChI

1S/C18H33ClN2O5S.ClH.H2O/c1-5-6-10-7-11(21(3)8-10)17(25)20-12(9(2)19)16-14(23)13(22)15(24)18(26-16)27-4;;/h9-16,18,22-24H,5-8H2,1-4H3,(H,20,25);1H;1H2/t9-,10+,11-,12+,13-,14+,15+,16+,18+;;/m0../s1

chave InChI

KWMXKEGEOADCEQ-WNNJHRBUSA-N

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Descrição geral

Clindamycin is a lincosamide antibiotic which is considered as a semisynthetic derivative of lincomycin. It is mainly used as an antimicrobial agent.
This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the issuing Pharmacopoeia.For further information and support please go to the website of the issuing Pharmacopoeia.

Aplicação

Clindamycin hydrochloride USP reference standard, intended for use in specified quality tests and assays as specified in the USP compendia.

Nota de análise

These products are for test and assay use only. They are not meant for administration to humans or animals and cannot be used to diagnose, treat, or cure diseases of any kind.  ​

Outras notas

Sales restrictions may apply.

Código de classe de armazenamento

11 - Combustible Solids

Classe de risco de água (WGK)

WGK 3

Ponto de fulgor (°F)

Not applicable

Ponto de fulgor (°C)

Not applicable


Certificados de análise (COA)

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D W Scott et al.
The Canadian veterinary journal = La revue veterinaire canadienne, 39(12), 753-756 (1998-12-23)
Clindamycin hydrochloride capsules (11 mg/kg body weight, q24 h) were administered orally to 20 dogs with deep staphylococcal pyoderma. Response to therapy was excellent in 100% of the dogs. Duration of therapy varied from 21 to 91 d, with an
D Gonzalez et al.
Clinical pharmacology and therapeutics, 96(4), 429-437 (2014-06-21)
Clindamycin is commonly prescribed to treat children with skin and skin-structure infections (including those caused by community-acquired methicillin-resistant Staphylococcus aureus (CA-MRSA)), yet little is known about its pharmacokinetics (PK) across pediatric age groups. A population PK analysis was performed in
Cutaneous botryomycosis diagnosed long after an arm injury.
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Journal of the American Academy of Dermatology, 71(4), e155-e156 (2014-09-16)
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The Journal of infectious diseases, 210(3), 473-482 (2014-02-15)
The Gram-positive human pathogen Staphylococcus aureus causes a variety of human diseases such as skin infections, pneumonia, and endocarditis. The micrococcal nuclease Nuc1 is one of the major S. aureus virulence factors and allows the bacterium to avoid neutrophil extracellular
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The American journal of emergency medicine, 32(7), 768-771 (2014-05-06)
The benefit of antibiotic prophylaxis for simple hand lacerations (lacerations that do not involve special structures) has not been adequately studied. To assess the feasibility of a randomized controlled trial to determine the role of antibiotic prophylaxis in emergency department

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