Pular para o conteúdo
Merck
Todas as fotos(1)

Documentos Principais

822854

TSKgel® SuperSW mAb HR (4 µm) HPLC Column

L x I.D. 30 m × 7.8 mm, diol phase

Sinônimo(s):

TSKgel® Size Exclusion (SW-Type) HPLC Column

Faça loginpara ver os preços organizacionais e de contrato
Todas as fotos(1)

About This Item

Código UNSPSC:
41115711

Nome do produto

Coluna de HPLC de exclusão por tamanho (tipo SW) TSKgel®, phase diol, L × I.D. 30 m × 7.8 mm, 4 μm particle size

Materiais

stainless steel

Agency

suitable for USP L20
suitable for USP L59

linha de produto

TSKgel®

fabricante/nome comercial

Tosoh SuperSW mAb HR, 22854

Parâmetros

≤0.5 M salt concentration
0-100% aqueous soluble organic solvents
1 mL/min flow rate
10-30 °C temperature
120 bar max. pressure

técnica(s)

HPLC: suitable

C × D.I.

30 m × 7.8 mm

Matriz

silica particle platform

Grupo ativo da matriz

diol phase

tamanho de partícula

4 μm

tamanho de poro

250 Å pore size

pH operacional

2.5-7.5

técnica de separação

size exclusion (SEC)

Procurando produtos similares? Visita Guia de comparação de produtos

Categorias relacionadas

Descrição geral

The TSKgel SuperSW and UltraSW mAb columns consist of three specialized columns designed for the separation and analysis of monoclonal antibodies (mAb). While mAbs can be analyzed using many different modes of HPLC, size exclusion is best to determine the level of aggregation, dimer formation, and fragmentation, making it the best method for heterogeneity studies. TSKgel SuperSW mAb HR columns are optimized for high resolution analysis of mAb monomer and dimer; these 30 cm x 7.8 mm ID slica-based stainless steel columns offer reduced lot-to-lot variation, long column life, reduction of unspecified adsorption, and superior recovery of aggregates. The TSKgel SuperSW mAb columns utilize a unique pore-controlled technology, which produces a shallow calibration curve in the molecular weight region of a typical monoclonal antibody. The calibration curve for the TSKgel SuperSW mAb HR column is similar to that of the industry-leading TSKgel G3000SWxl column and has a shallower slope than the TSKgel UltraSW Aggregate column around the molecular weight range of gamma-globulin. This shallow calibration curve produces high resolution separations.

Aplicação

TSKgel® superSW mAb HR HPLC column may be used in the separation of monoclonal antibodies using size exclusion chromatography (SEC).

forma física

Shipped in 0.05% NaN3 and 0.1 M Na2SO4 in 0.1 M phosphate buffer, pH 6.7.

Produtos recomendados

Discover LiChropur reagents ideal for HPLC or LC-MS analysis

Informações legais

TSKgel is a registered trademark of Tosoh Corporation

Escolha uma das versões mais recentes:

Certificados de análise (COA)

Lot/Batch Number

Lamentamos, não temos COA para este produto disponíveis online no momento.

Se precisar de ajuda, entre em contato Atendimento ao cliente

Já possui este produto?

Encontre a documentação dos produtos que você adquiriu recentemente na biblioteca de documentos.

Visite a Biblioteca de Documentos

Os clientes também visualizaram

Slide 1 of 8

1 of 8

SRT® SEC-300 Gel Filtration Column, 5 μm L × I.D. 30 cm × 7.8 mm, 5 μm particle size, stainless steel

Z777051

SRT® SEC-300 Gel Filtration Column, 5 μm

vibrant-m

808541

Coluna de HPLC TSKgel® G3000SWXL

Protein Standard Mix 15 - 600 kDa for size exclusion chromatography

Supelco

69385

Protein Standard Mix 15 - 600 kDa

TSKgel® UP-SW3000 HPLC Column phase diol, L × I.D. 15 cm × 4.6 mm, 2 μm particle size

80023449

TSKgel® UP-SW3000 HPLC Column

TSKgel® SuperSW Guard Column phase diol, L × I.D. 3.5 cm × 4.6 mm, 4 μm particle size

818762

TSKgel® SuperSW Guard Column

vibrant-m

808543

Coluna de guarda tipo SWXL TSKgel®

Coluna de HPLC TSKgel® G3000SWXL phase diol, L × I.D. 30 cm × 7.8 mm, 5 μm particle size

808540

Coluna de HPLC TSKgel® G3000SWXL

Coluna de HPLC TSKgel® G4000SWXL phase diol, L × I.D. 30 cm × 7.8 mm, 8 μm particle size

808542

Coluna de HPLC TSKgel® G4000SWXL

Oliver Seifert et al.
mAbs, 11(5), 919-929 (2019-04-06)
Multivalent mono- or bispecific antibodies are of increasing interest for therapeutic applications, such as efficient receptor clustering and activation, or dual targeting approaches. Here, we present a novel platform for the generation of Ig-like molecules, designated diabody-Ig (Db-Ig). The antigen-binding
Alexander Rau et al.
mAbs, 13(1), 1902034-1902034 (2021-03-24)
Dual targeting of surface receptors with bispecific antibodies is attracting increasing interest in cancer therapy. Here, we present a novel bivalent and bispecific antagonistic molecule (Dab-Fc) targeting human epidermal growth factors 2 and 3 (HER2 and HER3) derived from the

Artigos

Columns and Analytical Standards for Protein SEC

Size-exclusion chromatography (SEC) columns and ready-to-use standards facilitate method development and increase robustness of protein SEC methods.

Protocolos

Calibration Curves for TSKgel® SW mAb Columns

Calibration Curves for TSKgel® SW mAb Columns

Nossa equipe de cientistas tem experiência em todas as áreas de pesquisa, incluindo Life Sciences, ciência de materiais, síntese química, cromatografia, química analítica e muitas outras.

Entre em contato com a assistência técnica