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T3258

Sigma-Aldrich

Tetracycline

98.0-102.0% (HPLC)

Sinônimo(s):

Tetracycline Hydrate

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About This Item

Fórmula empírica (Notação de Hill):
C22H24N2O8 · xH2O
Número CAS:
60-54-8
Peso molecular:
444.43 (anhydrous basis)
Beilstein:
2230417
Número CE:
200-481-9
Número MDL:
MFCD00151232
Código UNSPSC:
51284017
ID de substância PubChem:
24900120
NACRES:
NA.85

Nível de qualidade

200

Ensaio

98.0-102.0% (HPLC)

forma

powder or crystals

condição de armazenamento

(Keep container tightly closed in a dry and well-ventilated place. Keep in a dry place.)

cor

faint yellow to dark yellow

espectro de atividade do antibiótico

Gram-negative bacteria
Gram-positive bacteria

Modo de ação

protein synthesis | interferes

temperatura de armazenamento

2-8°C

cadeia de caracteres SMILES

CN(C)[C@H]1[C@@H]2C[C@H]3C(=C(O)[C@]2(O)C(=O)C(C(N)=O)=C1O)C(=O)c4c(O)cccc4[C@@]3(C)O

InChI

1S/C22H24N2O8/c1-21(31)8-5-4-6-11(25)12(8)16(26)13-9(21)7-10-15(24(2)3)17(27)14(20(23)30)19(29)22(10,32)18(13)28/h4-6,9-10,15,25,27-28,31-32H,7H2,1-3H3,(H2,23,30)/t9-,10-,15-,21+,22-/m0/s1

chave InChI

OFVLGDICTFRJMM-WESIUVDSSA-N

Informações sobre genes

human ... CYP1A2(1544) , TERT(7015)

Procurando produtos similares? Visita Guia de comparação de produtos

Descrição geral

Chemical structure: tetracycline

Ações bioquímicas/fisiológicas

Mode of Action: Tetracycline passively diffuses through proin channels in the cell membrane, binding to 30S ribosomes and inhibits protein synthesis by preventing access of aminoacyl tRNA to the acceptor site on the mRNA-ribosome complex. It also binds to the bacterial 50S ribosomal subunit, altering the membrane and causing intracellular components to leak from bacterial cells. The inhibitory effects can be reversed by washing, suggesting that it is the reversibly bound antibiotic, and not the irreversibly bound drug, that is responsible for antibacterial action.

Mode of Resistance: The effects are inactivated via a loss of cell wall permeability.

Antimicrobial spectrum: Includes a wide range of antimicrobial activity against gram-positive and gram-negative bacteria.

Outras notas

Keep container tightly closed in a dry and well-ventilated place. Keep in a dry place

Palavra indicadora

Warning

Frases de perigo

H302,H361fd,H411

Classificações de perigo

Acute Tox. 4 Oral - Aquatic Chronic 2 - Repr. 2

Código de classe de armazenamento

11 - Combustible Solids

Classe de risco de água (WGK)

WGK 3

Ponto de fulgor (°F)

Not applicable

Ponto de fulgor (°C)

Not applicable

Equipamento de proteção individual

dust mask type N95 (US), Eyeshields, Gloves

Certificados de análise (COA)

Busque Certificados de análise (COA) digitando o Número do Lote do produto. Os números de lote e remessa podem ser encontrados no rótulo de um produto após a palavra “Lot” ou “Batch”.

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