SAB5701332

Anti- DNMT1 antibody produced in rabbit

• Código UNSPSC: 12352203
• NACRES: NA.43
• clone: monoclonal
• application: IHC; WB
• reatividade de espécies: rat, human, mouse
• técnica(s): immunohistochemistry: 1:50-1:200; western blot: 1:5000-1:8000

Propriedades

• fonte biológica: rabbit
• Nível de qualidade: 100
• tipo de produto de anticorpo: primary antibodies
• clone: monoclonal
• Formulário: liquid
• reatividade de espécies: rat, human, mouse
• concentração: 2.05 mg/mL
• técnica(s): immunohistochemistry: 1:50-1:200; western blot: 1:5000-1:8000
• nº de adesão UniProt: P26358
• Condições de expedição: wet ice
• temperatura de armazenamento: −20°C
• modificação pós-traducional do alvo: unmodified
• Informações sobre genes: human ... DNMT1(1786)

Descrição

Descrição geral

This gene encodes an enzyme that transfers methyl groups to cytosine nucleotides of genomic DNA. This protein is the major enzyme responsible for maintaining methylation patterns following DNA replication and shows a preference for hemi-methylated DNA. Methylation of DNA is an important component of mammalian epigenetic gene regulation. Aberrant methylation patterns are found in human tumors and associated with developmental abnormalities. Variation in this gene has been associated with cerebellar ataxia, deafness, and narcolepsy, and neuropathy, hereditary sensory, type IE. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jan 2016]

Imunogênio

A synthesized peptide derived from human DNMT1.

forma física

Buffer: PBS with 0.02% sodium azide,0.05% BSA,50% glycerol,pH7.3.

Informações de segurança

• Código de classe de armazenamento: 12 - Non Combustible Liquids
• Classe de risco de água (WGK): WGK 1
• Ponto de fulgor (°F): Not applicable
• Ponto de fulgor (°C): Not applicable