S9132

Spiramycin

• Sinônimo(s): Rovamycin, Formacidine
• Número CAS: 8025-81-8
• Número CE: 232-429-6
• Número MDL: MFCD01314545
• Código UNSPSC: 51283208
• ID de substância PubChem: 24899826
• NACRES: NA.85

Propriedades

• forma: powder
• atividade óptica: [α]/D -85 to -80° in water (Specific rotation (dry basis))
• potência: ≥4100 I.U. per mg (dry basis)
• condição de armazenamento: (Keep container tightly closed in a dry and well-ventilated place.)
• cor: white to light yellow
• solubilidade: methanol: soluble
• traços de cátion: heavy metals: ≤20 ppm
• espectro de atividade do antibiótico: Gram-positive bacteria
• Modo de ação: protein synthesis | interferes
• temperatura de armazenamento: 2-8°C
• cadeia de caracteres SMILES: CO[C@H]1[C@H](O)CC(=O)O[C@H](C)C\C=C\C=C\[C@H](OC2CCC(C(C)O2)N(C)C)[C@H](C)C[C@H](CC=O)[C@@H]1OC3OC(C)C(OC4CC(C)(O)C(O)C(C)O4)C(C3O)N(C)C
• InChI: 1S/C43H74N2O14/c1-24-21-29(19-20-46)39(59-42-37(49)36(45(9)10)38(27(4)56-42)58-35-23-43(6,51)41(50)28(5)55-35)40(52-11)31(47)22-33(48)53-25(2)15-13-12-14-16-32(24)57-34-18-17-30(44(7)8)26(3)54-34/h12-14,16,20,24-32,34-42,47,49-51H,15,17-19,21-23H2,1-11H3/b13-12+,16-14+/t24-,25-,26?,27?,28?,29+,30?,31-,32+,34?,35?,36?,37?,38?,39+,40+,41?,42?,43?/m1/s1
• chave InChI: ACTOXUHEUCPTEW-JMRHEKERSA-N

Descrição

Descrição geral

Chemical structure: macrolide

Aplicação

Spiramycin is a macrolide antibiotic that is commonly used to treat infections of soft tissues. It has been used to treat bronchopulmonary infections in adults and has been used to study septicemia in mice .

Ações bioquímicas/fisiológicas

Spiramycin is a 16-membered ring macrolide antibiotic from Streptomyces ambofaciens. It inhibits bacterial protein synthesis at the level of peptidy-tRNA dissociation from ribosomes. It is mainly used against Gram-positive bacteria.

Qualidade

A mixture of Spiramycin I, II and III.

Outras notas

Keep container tightly closed in a dry and well-ventilated place.

Informações de segurança

• Código de classe de armazenamento: 11 - Combustible Solids
• Classe de risco de água (WGK): WGK 1
• Ponto de fulgor (°F): Not applicable
• Ponto de fulgor (°C): Not applicable
• Equipamento de proteção individual: Eyeshields, Gloves, type N95 (US)