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Documentos Principais

PHG0003

SAFC

MES

Fabricação farmacêutica

Sinônimo(s):

Ácido 2-(N-morfolino) etanossulfônico, Ácido 4-morfolino etanossulfônico

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About This Item

Fórmula empírica (Notação de Hill):
C6H13NO4S · xH2O
Número CAS:
Peso molecular:
195.24 (anhydrous basis)
Número MDL:
Código UNSPSC:
12161700
NACRES:
NA.21

fonte biológica

synthetic

Nível de qualidade

Formulário

powder

técnica(s)

cell culture | mammalian: suitable

Impurezas

Endotoxin, microbial, and trace metals; tested

faixa de pH útil

5.5-6.7

pKa 

6.1

adequação

suitable for manufacturing use

atividade externa

Cytotoxicity, DNase, NICKase, RNase, and Protease; tested

cadeia de caracteres SMILES

O.OS(=O)(=O)CCN1CCOCC1

InChI

1S/C6H13NO4S.H2O/c8-12(9,10)6-3-7-1-4-11-5-2-7;/h1-6H2,(H,8,9,10);1H2

chave InChI

MIIIXQJBDGSIKL-UHFFFAOYSA-N

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Descrição geral

Our SAFC® portfolio of high-quality raw materials for use in biopharmaceutical processing withstands strict quality control procedures plus the documentation and expertise to help our customers meet requirements as defined by the M-Clarity Program.

M-Clarity Program

Buffer quality is vital for the success of biopharmaceutical processes, because buffers are indispensable in nearly every production step.

Our broad portfolio of buffer materials manufactured under appropriate controls is tailored to your needs. Ranging from non-GMP grades for low-risk application, to IPEC-PQG GMP for higher-risk applications, we have products covering all your manufacturing needs.

Aplicação

MES is a biological buffer often referred to as a “Good′s” buffer. The pKa of MES is 5.96 which makes MES an ideal candidate for medias and protein based buffer formulations to maintain a stable environment in solution. MES is considered to be non-toxic to culture cell lines, highly water soluble and provides high-solution clarity.

MES is used in cell culture media, biopharmaceutical buffer formulations (both upstream and downstream), and diagnostic reagents. MES based buffers are used in purification bioprocesses of antibodies, peptides, proteins, blood components and growth factors.

Informações legais

SAFC is a registered trademark of Merck KGaA, Darmstadt, Germany

substituído por

Nº do produto
Descrição
Preços

Código de classe de armazenamento

11 - Combustible Solids

Classe de risco de água (WGK)

WGK 3

Ponto de fulgor (°F)

Not applicable

Ponto de fulgor (°C)

Not applicable


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The mechanisms of cold adaptation by fungi remain unknown. This topic is of high interest due to the emergence of white-nose syndrome (WNS), a skin infection of hibernating bats caused by Pseudogymnoascus destructans (Pd). Recent studies indicated that apart from

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