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Key Documents

P9158

Sigma-Aldrich

Pyridoxamine dihydrochloride

BioReagent, suitable for cell culture

Sinônimo(s):

4-(Aminomethyl)-5-hydroxy-6-methyl-3-pyridinemethanol dihydrochloride

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About This Item

Fórmula empírica (Notação de Hill):
C8H12N2O2 · 2HCl
Número CAS:
Peso molecular:
241.11
Beilstein:
3632748
Número CE:
Número MDL:
Código UNSPSC:
12352205
ID de substância PubChem:
NACRES:
NA.75

fonte biológica

synthetic (organic)

linha de produto

BioReagent

Ensaio

≥98%

forma

powder

peso molecular

Mw 241.11 g/mol

técnica(s)

cell culture | mammalian: suitable

cor

white to off-white

pf

224-226 °C (dec.) (lit.)

solubilidade

water: soluble 50 mg/mL, clear, colorless to faintly yellow

temperatura de armazenamento

−20°C

cadeia de caracteres SMILES

Cl[H].Cl[H].Cc1ncc(CO)c(CN)c1O

InChI

1S/C8H12N2O2.2ClH/c1-5-8(12)7(2-9)6(4-11)3-10-5;;/h3,11-12H,2,4,9H2,1H3;2*1H

chave InChI

HNWCOANXZNKMLR-UHFFFAOYSA-N

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Aplicação

Use in mammalian cell culture as an alternative to pyridoxine or pyridoxal. Vitamin B6 is a required component of cell culture media. Historically, media have been supplemented with vitamin B6 in the aldehyde form, pyridoxal. While this is a biologically active form of vitamin B6, it is unstable in liquid media. When cells are able to utilize either pyridoxine and/or pyridoxamine, they are preferred supplement versus pyridoxal. A number of classical media are now offered with a choice between pyridoxal and pyridoxine as the vitamin A source.

Código de classe de armazenamento

11 - Combustible Solids

Classe de risco de água (WGK)

WGK 2

Ponto de fulgor (°F)

Not applicable

Ponto de fulgor (°C)

Not applicable

Equipamento de proteção individual

dust mask type N95 (US), Eyeshields, Gloves


Certificados de análise (COA)

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Artigos

This page segues to comprehensive insights on how Vitamin B6, Pyridoxal and Pyridoxine affect the performance of serum-free, protein-free cell culture systems used for biomanufacturing heterologous proteins including monoclonal antibodies. The page introduces the in vitro chemistry and biochemistry of pyridoxal, pyridoxine.

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