P5069

Prostaglandin F_2α tris salt

synthetic, suitable for cell culture

• Sinônimo(s): (5Z,9α,11α,13E,15S)-9,11,15-Trihydroxyprosta-5,13-dienoic acid tris salt, PGF_2α−Tris
• Fórmula empírica (Notação de Hill): C₂₀H₃₄O₅ · C₄H₁₁NO₃
• Número CAS: 38562-01-5
• Peso molecular: 475.62
• Beilstein: 4087514
• Número CE: 254-002-3
• Número MDL: MFCD00077863
• Código UNSPSC: 12352209
• ID de substância PubChem: 24898587
• NACRES: NA.77

Propriedades

• fonte biológica: synthetic
• Ensaio: ≥99%
• Formulário: powder
• técnica(s): cell culture | mammalian: suitable
• solubilidade: ethanol: 50 mg/mL, clear, colorless
• Condições de expedição: ambient
• temperatura de armazenamento: −20°C
• cadeia de caracteres SMILES: NC(CO)(CO)CO.[H][C@]1(C\C=C/CCCC(O)=O)[C@@H](O)C[C@@H](O)[C@]1([H])\C=C\[C@@H](O)CCCCC
• InChI: 1S/C20H34O5.C4H11NO3/c1-2-3-6-9-15(21)12-13-17-16(18(22)14-19(17)23)10-7-4-5-8-11-20(24)25;5-4(1-6,2-7)3-8/h4,7,12-13,15-19,21-23H,2-3,5-6,8-11,14H2,1H3,(H,24,25);6-8H,1-3,5H2/b7-4-,13-12+;/t15-,16+,17+,18-,19+;/m0./s1
• chave InChI: IYGXEHDCSOYNKY-RZHHZEQLSA-N
• Informações sobre genes: human ... PTGFR(5737)

Descrição

Ações bioquímicas/fisiológicas

Luteolytic prostaglandin that induces parturition. Potent vasoconstrictor of pulmonary, coronary, and cerebral arteriole beds.

Luteolytic prostaglandin that induces parturition. Potent vasoconstrictor of pulmonary, coronary, and cerebral arteriole beds. A positive feedback loop between endometrial PG F_2α and luteal oxytocin is responsible for completion of luteolysis.

Luteolytic prostaglandin that induces parturition. Potent vasoconstrictor of pulmonary, coronary, and cerebral arteriole beds. Also stimulates contraction of smooth muscle, such as in bronchi, with possible involvement in asthma. This effect is at least partially mediated through tachykinin release.

Prostaglandin F2α is induced by uterine-produced oxytocin and acts on the corpus luteum to cause luteolysis and inhibit progesterone production.

Informações de segurança

• Pictogramas: GHS08,GHS07
• Palavra indicadora: Danger
• Frases de perigo: H302,H360FD
• Declarações de precaução: P202 - P264 - P280 - P301 + P312 - P308 + P313 - P405
• Classificações de perigo: Acute Tox. 4 Oral - Repr. 1B
• Código de classe de armazenamento: 6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects
• Classe de risco de água (WGK): WGK 3
• Equipamento de proteção individual: Eyeshields, Gloves, type P3 (EN 143) respirator cartridges