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P1639

Sigma-Aldrich

Patulin

≥98.0% (HPLC)

Sinônimo(s):

Clavacin, Clavatin, Expansine, Gigantin, Leucopin, Mycoine C3, Terinin, 4-Hydroxy-4H-furo[3,2-c]pyran-2(6H)-one

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About This Item

Fórmula empírica (Notação de Hill):
C7H6O4
Número CAS:
149-29-1
Peso molecular:
154.12
Beilstein:
149675
Número CE:
205-735-2
Número MDL:
MFCD00005858
Código UNSPSC:
51102829
ID de substância PubChem:
24898227
NACRES:
NA.85

Nível de qualidade

300

Ensaio

≥98.0% (HPLC)

forma

powder

solubilidade

water: 9-11 mg/mL

espectro de atividade do antibiótico

fungi

Modo de ação

cell membrane | interferes

temperatura de armazenamento

−20°C

cadeia de caracteres SMILES

OC1OCC=C2OC(=O)C=C12

InChI

1S/C7H6O4/c8-6-3-4-5(11-6)1-2-10-7(4)9/h1,3,7,9H,2H2

chave InChI

ZRWPUFFVAOMMNM-UHFFFAOYSA-N

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Descrição geral

Patulin is a mycotoxin produced by a variety of molds, such as, Aspergillus and Penicillium. It is commonly found in apples. It is used as an inhibitor of potassium uptake and as an inducer of ion flux across cell membranes, potentially involving Na+-K+ dependent ATPase and to induce intra- and intermolecular protein crosslinking.

Aplicação

Patulin has been used:
  • to study patulin contamination of bottled wine
  • in DNA-damaging activity of patulin in Escherichia coli
  • in molecular cloning and functional characterization of two CYP619 cytochrome P450s involved in biosynthesis of patulin in Aspergillus clavatus

Ações bioquímicas/fisiológicas

Mycotoxin with anti-bacterial, potassium uptake inhibitory, and possibly carcinogenic activities. It is used as an inhibitor of potassium uptake and as an inducer of ion flux across cell membranes, potentially involving Na+-K+ dependent ATPase and to induce intra- and intermolecular protein crosslinking.

Outras notas

Keep container tightly closed in a dry and well-ventilated place.

Pictogramas

Skull and crossbones
GHS06

Palavra indicadora

Danger

Frases de perigo

H300,H315

Classificações de perigo

Acute Tox. 2 Oral - Skin Irrit. 2

Código de classe de armazenamento

6.1A - Combustible acute toxic Cat. 1 and 2 / very toxic hazardous materials

Classe de risco de água (WGK)

WGK 3

Equipamento de proteção individual

Eyeshields, Gloves

Certificados de análise (COA)

Busque Certificados de análise (COA) digitando o Número do Lote do produto. Os números de lote e remessa podem ser encontrados no rótulo de um produto após a palavra “Lot” ou “Batch”.

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