O5500
Osmium tetroxide
Sealed ampule.
Sinônimo(s):
Osmium(VIII)-oxide, ‘Osmic acid’
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About This Item
Fórmula linear:
OsO4
Número CAS:
Peso molecular:
254.23
Número CE:
Número MDL:
Código UNSPSC:
12171500
ID de substância PubChem:
NACRES:
NA.47
Produtos recomendados
grau
for analytical purposes
densidade de vapor
8.8 (vs air)
pressão de vapor
7 mmHg ( 20 °C)
Formulário
powder
adequação da reação
reagent type: oxidant
p.e.
130 °C (lit.)
pf
39.5-41 °C (lit.)
cadeia de caracteres SMILES
O=[Os](=O)(=O)=O
InChI
1S/4O.Os
chave InChI
VUVGYHUDAICLFK-UHFFFAOYSA-N
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Descrição geral
Osmium tetroxide (OsO4) is a heavy tetrahedral, symmetrical molecule composed of osmium, a third-row transition metal. Osmium tetroxide is both a dye, and a non-coagulant fixative agent in electron microscopy primarily used for the examination of biological tissue components in the histopathology laboratory. Specimens are postfixed with osmium testroxide to ensure preservation of the lipids.
Aplicação
Osmium tetroxide has been used as a fixative reagent for Brevibacterium mcbrellneri, and curcumin treated human lung cancer cell lines′ observation with a scanning electron microscope. It is also suitable as a fixative for ultrastructural analysis of Toxoplasma gondii′s skeletal muscle cells.
Ações bioquímicas/fisiológicas
Osmium tetroxide chemically combines with lipids making them insoluble; only 7% of the lipids can be extracted after the fixation. Therefore, the cell membranes comprising phospholipids become black and electron-dense after fixation in osmium tetroxide. It is also used to fix small amount of fat maintained in sections during paraffin processing.
Outras notas
Due to the hazardous nature of osmium tetroxide, it is recommended to use an ampule opener when using this chemical.
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Nº do produto
Descrição
Preços
Palavra indicadora
Danger
Frases de perigo
Declarações de precaução
Classificações de perigo
Acute Tox. 1 Dermal - Acute Tox. 2 Inhalation - Acute Tox. 2 Oral - Eye Dam. 1 - Skin Corr. 1B
Código de classe de armazenamento
6.1A - Combustible acute toxic Cat. 1 and 2 / very toxic hazardous materials
Classe de risco de água (WGK)
WGK 1
Ponto de fulgor (°F)
Not applicable
Ponto de fulgor (°C)
Not applicable
Equipamento de proteção individual
Eyeshields, Faceshields, Gloves, type P3 (EN 143) respirator cartridges
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