O2375

L-Ornithine monohydrochloride

≥99%

• Sinônimo(s): (S)-2,5-Diaminopentanoic acid monohydrochloride
• Fórmula empírica (Notação de Hill): C₅H₁₂N₂O₂ · HCl
• Número CAS: 3184-13-2
• Peso molecular: 168.62
• Beilstein: 3625847
• Número CE: 221-678-6
• Número MDL: MFCD00064562
• Código UNSPSC: 12352209
• ID de substância PubChem: 24897960
• NACRES: NA.26

Propriedades

• product name: L-Ornithine monohydrochloride, ≥99%
• Nível de qualidade: 200
• Ensaio: ≥99%
• forma: powder
• Impurezas: ammonia and citrulline, essentially free
• cor: white
• aplicação(ões): cell analysis
• cadeia de caracteres SMILES: Cl.NCCC[C@H](N)C(O)=O
• InChI: 1S/C5H12N2O2.ClH/c6-3-1-2-4(7)5(8)9;/h4H,1-3,6-7H2,(H,8,9);1H/t4-;/m0./s1
• chave InChI: GGTYBZJRPHEQDG-WCCKRBBISA-N

Descrição

Aplicação

L-Ornithine monohydrochloride has been used to study the blocking effect of L-ornithine on the transport system that carries L-arginine for the overproduction of nitric oxide during lipopolysaccharide induced endotoxemia in rat model. It has also been used in decarboxylation test of amino acids.

Ações bioquímicas/fisiológicas

L-Ornithine is a product of arginase degradation and plays an important role in ammonia metabolism via the urea cycle. In mammals, ornithine serves as a precursor for polyamines and proline biosynthesis. Spermine synthesized from ornithine, is an abundant polyamine observed in tumors such as breast carcinomas. Administration of L-ornithine is known to improve subjective index of sleep quality. L-ornithine reduces the cortisol/DHEA-S (dehydroepiandrosterone) ratio, that is associated with stress. In mice, L-ornithine is found to affect the levels of plasma growth hormone, corticosterone and melatonin levels in mice.

Outras notas

Product of arginine degradation by arginase

Informações de segurança

• Código de classe de armazenamento: 11 - Combustible Solids
• Classe de risco de água (WGK): WGK 1
• Ponto de fulgor (°F): Not applicable
• Ponto de fulgor (°C): Not applicable
• Equipamento de proteção individual: Eyeshields, Gloves, type N95 (US)