N8159
Albumin, Nitrated from bovine serum
lyophilized powder
Sinônimo(s):
Nitrated BSA
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About This Item
Produtos recomendados
fonte biológica
bovine
Nível de qualidade
forma
lyophilized powder
técnica(s)
immunoblotting: suitable
nº de adesão UniProt
Condições de expedição
wet ice
temperatura de armazenamento
−20°C
Informações sobre genes
bovine ... ALB(280717)
Categorias relacionadas
Descrição geral
Albumin, Nitrated (Nitrated BSA), is prepared by chemical modification of bovine serum albumin (BSA) by peroxynitrite. Peroxynitrite (ONOO-), a potent oxidant is an important member of the family of reactive oxygen and nitrogen species.
Aplicação
Positive control in immunoblotting assays for Anti-Nitrotyrosine (Sigma Product Number N 0409).
Ações bioquímicas/fisiológicas
Peroxynitrite promotes the nitration of tyrosine residues in proteins linked, oxidation of redox metal centers, DNA, lipids and nitrosation of cysteine residues in proteins, suggesting that peroxynitrite plays a major role in oxidative cellular damage. Peroxynitrite has been implicated in the pathogenesis of several inflammatory, infectious and degenerative human disease. These include neurological conditions such as Alzheimer′s disease, amyotrophic lateral sclerosis (ALS), the pathogenesis of asthma, atherosclerosis, and a variety of conditions precipitated by endothelial injury.
forma física
Lyophilized from 0.01 M phosphate buffered saline, pH 7.4
Nota de preparo
Bovine serum albumin (BSA) nitrated with peroxynitrite.
Nota de análise
Does not contain sodium azide
Exoneração de responsabilidade
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
Código de classe de armazenamento
10 - Combustible liquids
Classe de risco de água (WGK)
WGK 3
Ponto de fulgor (°F)
Not applicable
Ponto de fulgor (°C)
Not applicable
Certificados de análise (COA)
Busque Certificados de análise (COA) digitando o Número do Lote do produto. Os números de lote e remessa podem ser encontrados no rótulo de um produto após a palavra “Lot” ou “Batch”.
Já possui este produto?
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Lai H and Yen GC
Bioscience, Biotechnology, and Biochemistry, 66(1), 22-28 (2002)
The Intracellular Redox Stress Caused by Hexavalent Chromium is Selective for Proteins that Have Key Roles in Cell Survival and Thiol Redox Control
Judith M
Toxicology (2011)
Nitric oxide and peroxynitrite in health and disease
Pacher P, et al.
Physiological Reviews, 87(1), 315-424 (2007)
Péter Borbély et al.
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