N7785

β-Nicotinamide adenine dinucleotide 2′-phosphate reduced tetrasodium salt

vial of 10 mg, ~95%

• Sinônimo(s): β-NADPH, 2′-NADPH, Coenzyme II reduced tetrasodium salt, Dihydronicotinamide adenine dinucleotide phosphate tetrasodium salt, NADPH Na₄, TPNH₂ Na₄, Triphosphopyridine nucleotide reduced tetrasodium salt
• Fórmula empírica (Notação de Hill): C₂₁H₂₆N₇Na₄O₁₇P₃
• Peso molecular: 833.35
• Número CE: 214-664-6
• Número MDL: MFCD00036263
• Código UNSPSC: 41106305
• ID de substância PubChem: 24897841
• NACRES: NA.51

Propriedades

• Ensaio: ~95%
• Nível de qualidade: 200
• forma: powder
• embalagem: vial of 10 mg
• InChI: 1S/C21H30N7O17P3.4Na/c22-17-12-19(25-7-24-17)28(8-26-12)21-16(44-46(33,34)35)14(30)11(43-21)6-41-48(38,39)45-47(36,37)40-5-10-13(29)15(31)20(42-10)27-3-1-2-9(4-27)18(23)32;;;;/h1,3-4,7-8,10-11,13-16,20-21,29-31H,2,5-6H2,(H2,23,32)(H,36,37)(H,38,39)(H2,22,24,25)(H2,33,34,35);;;;/q;4*+1/p-4/t10-,11+,13-,14+,15-,16+,20-,21+;;;;/m0..../s1
• chave InChI: WYWWVJHQDVCHKF-MPUNMZHWSA-J

Descrição

Aplicação

β-Nicotinamide adenine dinucleotide 2′-phosphate (NADP+) and β-Nicotinamide adenine dinucleotide 2′-phosphate, reduced (NADPH) comprise a coenzyme redox pair (NADP+:NADPH) involved in a wide range of enzyme catalyzed oxidation reduction reactions. The NADP+/NADPH redox pair facilitates electron transfer in anabolic reactions such as lipid and cholesterol biosynthesis and fatty acyl chain elongation. The NADP⁺/NADPH redox pair is used in a variety of antioxidation mechanism where it protects agains reactive oxidation species accumulation. NADPH is generated in vivio by the pentose phosphate pathway (PPP).

β-Nicotinamide adenine dinucleotide 2′-phosphate reduced tetrasodium salt has been used in the Griess reagent assay of culture medium to reduce nitrate to nitrite and in glutathione peroxidase assay.

Ações bioquímicas/fisiológicas

β-Nicotinamide adenine dinucleotide 2′-phosphate (NADP⁺) and β-Nicotinamide adenine dinucleotide 2′-phosphate, reduced (NADPH) comprise a coenzyme redox pair (NADP⁺:NADPH) involved in a wide range of enzyme catalyzed oxidation reduction reactions. The NADP⁺/NADPH redox pair facilitates electron transfer in anabolic reactions such as lipid and cholesterol biosynthesis and fatty acyl chain elongation. The NADP⁺/NADPH redox pair is used in a variety of antioxidation mechanism where it protects agains reactive oxidation species accumulation. NADPH is generated in vivo by the pentose phosphate pathway (PPP).

Nota de preparo

Chemically reduced

Outras notas

Packaged based on NADPH content as determined by UV-Vis.

Informações de segurança

• Código de classe de armazenamento: 11 - Combustible Solids
• Classe de risco de água (WGK): WGK 3
• Ponto de fulgor (°F): Not applicable
• Ponto de fulgor (°C): Not applicable
• Equipamento de proteção individual: Eyeshields, Gloves, type N95 (US)