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Documentos Principais

N6877

Sigma-Aldrich

L-Norleucine

≥98% (TLC)

Sinônimo(s):

(S)-(+)-2-Aminohexanoic acid, (S)-2-Aminocaproic acid

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About This Item

Fórmula linear:
CH3(CH2)3CH(NH2)CO2H
Número CAS:
Peso molecular:
131.17
Beilstein:
1721750
Número CE:
Número MDL:
Código UNSPSC:
12352209
eCl@ss:
32160406
ID de substância PubChem:
NACRES:
NA.26

Nível de qualidade

Ensaio

≥98% (TLC)

Formulário

powder

cor

white

pf

>300 °C (lit.)

aplicação(ões)

detection

cadeia de caracteres SMILES

CCCC[C@H](N)C(O)=O

InChI

1S/C6H13NO2/c1-2-3-4-5(7)6(8)9/h5H,2-4,7H2,1H3,(H,8,9)/t5-/m0/s1

chave InChI

LRQKBLKVPFOOQJ-YFKPBYRVSA-N

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Aplicação


  • l-norleucine on high glucose-induced insulin sensitivity and mitochondrial function in skeletal muscle cells. This study explores the beneficial effects of L-Norleucine on insulin sensitivity and mitochondrial function, underlining its potential in metabolic pathway research and its application in managing diabetes through targeted amino acid therapy (Ding et al., 2024).

Ações bioquímicas/fisiológicas

L-Norleucine is a synthetic amino acid commonly used as an internal standard.

Outras notas

Non-essential amino acid.

Pictogramas

Exclamation mark

Palavra indicadora

Warning

Frases de perigo

Classificações de perigo

Skin Sens. 1

Código de classe de armazenamento

11 - Combustible Solids

Classe de risco de água (WGK)

WGK 3

Ponto de fulgor (°F)

Not applicable

Ponto de fulgor (°C)

Not applicable

Equipamento de proteção individual

dust mask type N95 (US), Eyeshields, Faceshields, Gloves


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Following the studies of urea denaturation of β-hairpins using molecular dynamics, in this paper, molecular dynamics simulations of two peptides, a 35 residue three helix bundle villin headpiece protein HP-35 and its doubly norleucine-substituent mutant (Lys24Nle/Lys29Nle) HP-35 NleNle, were undertaken
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