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Key Documents

L5900

Sigma-Aldrich

Linoleic Acid-Water Soluble

powder, BioReagent, suitable for cell culture

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About This Item

Código UNSPSC:
12352211
NACRES:
NA.75

fonte biológica

plant (Safflower oil)

linha de produto

BioReagent

forma

powder

técnica(s)

cell culture | mammalian: suitable

solubilidade

H2O: 50 mg/mL

temperatura de armazenamento

−20°C

Aplicação

Linoleic acid-water soluble has been used as a component of fatting media for the in vitro steatosis induction of primary human hepatocytes (PHH).

Ações bioquímicas/fisiológicas

Linoleic acid (LA) is an arachidonic acid precursor, which is present in vegetable oils. It enhances wound healing in diabetic rats. LA triggers tumor and apoptosis in colorectal cancer cells. The levels of LA in adipose tissue and platelets are associated with coronary artery disease. Linoleic acid binds to molecules, such as bovine serum albumin (BSA) or cyclodextrin for use in cell culture.

Outras notas

Contains approx. 30 mg of linoleic acid per gram; balance methyl-β-cyclodextrin.
Package size based on linoleic acid content.

Pictogramas

Exclamation mark
GHS07

Palavra indicadora

Warning

Frases de perigo

H319

Declarações de precaução

P305 + P351 + P338

Classificações de perigo

Eye Irrit. 2

Código de classe de armazenamento

11 - Combustible Solids

Classe de risco de água (WGK)

WGK 3

Ponto de fulgor (°F)

Not applicable

Ponto de fulgor (°C)

Not applicable

Certificados de análise (COA)

Busque Certificados de análise (COA) digitando o Número do Lote do produto. Os números de lote e remessa podem ser encontrados no rótulo de um produto após a palavra “Lot” ou “Batch”.

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B R Abdel-Halim
Theriogenology, 114, 143-148 (2018-04-07)
The current study was conducted to investigate the effect of linoleic acid-treated oocytes during in vitro maturation (IVM) on cumulus cell expansion, oocyte nuclear maturation, blastocyst development and DNA damage of cumulus cells and how its effects were alleviated by supplementation
Chemical-defined and albumin-free generation of human atrial and ventricular myocytes from human pluripotent stem cells
Pei F, et al.
Stem Cell Research, 19, 94-103 (2017)
Enhancement effects of BSA and linoleic acid on hybridoma cell growth and antibody production
Cell Culture Engineering IV, 51-56 (1994)
Takashi Okumura et al.
Oncotarget, 8(11), 18280-18295 (2017-04-15)
Pancreatic cancer progression involves components of the tumor microenvironment, including stellate cells, immune cells, endothelial cells, and the extracellular matrix. Although peripancreatic fat is the main stromal component involved in extra-pancreatic invasion, its roles in local invasion and metastasis of
María Alejandra Moreno et al.
Journal of ethnopharmacology, 216, 283-294 (2018-01-09)
The Argentinean medicinal plant Tetraglochin andina Ciald, formerly classified as T. cristatum (Britton) Rothm is used in traditional medicine by inhabitants from Argentinean northwestern highlands (Puna) to treat candidiasis and as anti-inflammatory. To assess the potential of the crude drug
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