L1045

LY-354740 hydrate

≥98% (HPLC)

• Sinônimo(s): (1S,2S,5R,6S)-2-Aminobicyclo[3.1.0]hexane-2,6-dicarboxy lic acid, Eglumegad, Eglumetad, LY-354740
• Fórmula empírica (Notação de Hill): C₈H₁₁NO₄ · xH₂O
• Peso molecular: 185.18 (anhydrous basis)
• Código UNSPSC: 12352209
• eCl@ss: 32160406
• NACRES: NA.77

Propriedades

• Nível de qualidade: 100
• Ensaio: ≥98% (HPLC)
• Formulário: solid
• solubilidade: deionized water: 8 mg/mL
• originador: Eli Lilly
• temperatura de armazenamento: room temp

Descrição

Aplicação

LY-354740 hydrate has been used as a metabotropic glutamate receptor group II/III agonist to study its behavioral effectsof electric shock on Gammarus fossarum.

Ações bioquímicas/fisiológicas

LY-354740 is a highly selective and potent agonist of group II mGlu (metabotropic glutamate) receptors. It displays antianxiety and antiaddictive activity in vivo. It?s orally and systemically active. It is anxiolytic and inhibits symptoms of morphine withdrawal in morphine-dependent mice.

Características e benefícios

This compound is a featured product for Neuroscience research. Click here to discover more featured Neuroscience products. Learn more about bioactive small molecules for other areas of research at sigma.com/discover-bsm.

This compound is featured on the Glutamate Receptors (G Protein Family) page of the Handbook of Receptor Classification and Signal Transduction. To browse other handbook pages, click here.

This compound was developed by Eli Lilly. To browse the list of other pharma-developed compounds and Approved Drugs/Drug Candidates, click here.

Informações de segurança

• Pictogramas: GHS07
• Palavra indicadora: Warning
• Frases de perigo: H302
• Declarações de precaução: P264 - P270 - P301 + P312 - P501
• Classificações de perigo: Acute Tox. 4 Oral
• Código de classe de armazenamento: 11 - Combustible Solids
• Classe de risco de água (WGK): WGK 3
• Ponto de fulgor (°F): Not applicable
• Ponto de fulgor (°C): Not applicable