L0636
Lectin from Triticum vulgaris (wheat)
suitable for cell culture, BioReagent, lyophilized powder
Sinônimo(s):
WGA, Wheat germ agglutinin
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About This Item
Produtos recomendados
esterilidade
aseptically processed
Nível de qualidade
linha de produto
BioReagent
Formulário
lyophilized powder
técnica(s)
cell culture | mammalian: suitable
Impurezas
salt, essentially free
temperatura de armazenamento
2-8°C
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Descrição geral
Lectin from Triticum vulgaris (wheat) is a dimeric glycoprotein of 36 kDa. It belongs to the family of chitin-binding proteins. Glycosylated precursor of lectin is synthesized in endoplasmic reticulum.
Aplicação
Lectin from Triticum vulgaris (wheat) has been used:
- to conjugate with N-hydroxysuccinimide (NHS) dye
- to inhibit nuclear import
- to inhibit the nuclear pore of human cervical carcinoma HeLa and SiHa cells
Ações bioquímicas/fisiológicas
Lectin from Triticum vulgaris (wheat) possessing four binding sites is specific for N-acetyl-d-glucosamine and N-acetyl-d-neuraminic acid (sialic acid) residues. Lectins also function as a fungicide. They also possess anti-nutritive effects.
WGA is not blood group specific but has an affinity for N-acetyl-β-D-glucosaminyl residues and N-acetyl-β-D-glucosamine oligomers. WGA contains no protein-bound carbohydrate.
Outras notas
Highly purified
Nota de preparo
Conjugates are prepared from affinity purified lectin.
Código de classe de armazenamento
11 - Combustible Solids
Classe de risco de água (WGK)
WGK 3
Ponto de fulgor (°F)
Not applicable
Ponto de fulgor (°C)
Not applicable
Equipamento de proteção individual
Eyeshields, Gloves, type N95 (US)
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International journal of nanomedicine, 7, 5215-5234 (2012-10-17)
Gold nanoparticles modified with the nuclear localization signal from simian virus 40 large T antigen (GNP-PEG/SV40) accumulate on the cytoplasmic side of the nuclear membrane in HeLa cells. Accumulation of GNP-PEG/SV40 around the nucleus blocks nucleocytoplasmic transport and prevents RNA
Nuclear localization of Tob is important for regulation of its antiproliferative activity
Oncogene, 23, 6630-6630 (2004)
Effects of wheat germ agglutinin on human gastrointestinal epithelium: insights from an experimental model of immune/epithelial cell interaction
Toxicology and Applied Pharmacology, 237, 146-153 (2009)
Super-multiplex vibrational imaging
Nature, 544, 465-465 (2017)
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