L7647
Concanavalin A from Canavalia ensiformis (Jack bean)
Type VI, lyophilized powder
Sinônimo(s):
Con A
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About This Item
Produtos recomendados
fonte biológica
Canavalia ensiformis
Nível de qualidade
tipo
Type VI
Formulário
lyophilized powder
potência
≤20 μg per mL agglutination activity
Impurezas
Carbohydrate, essentially free
salt, essentially free
solubilidade
water: 1 % (w/v)
temperatura de armazenamento
−20°C
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Aplicação
Concanavalin A from Canavalia ensiformis (Jack bean) has been used for developing zwitterion-immobilized molecularly imprinted polymers (ziMIPs) for protein crystallization. It has been also used in the preparation of protein loaded microgels to prevent enzymatic degradation of microgels for monitoring by confocal laser scanning microscope (CLSM).
Ações bioquímicas/fisiológicas
Con A is not blood group specific but has an affinity for terminal α-D-mannosyl and α-D-glucosyl residues. Ca2+ and Mn2+ ions are required for activity. Con A dissociates into dimers at pH 5.6 or below. Between pH 5.8 and pH 7.0, Con A exists as a tetramer; above pH 7.0 higher aggregates are formed. Con A exhibits mitogenic activity which is dependent on its degree of aggregation. Succinylation results in an active dimeric form which remains a dimer above pH 5.6.
Nota de preparo
Highly purified by specific affinity chromatography.
Nota de análise
Agglutination activity: Determined from serial dilutions of a 1 mg/mL solution (this activity is the lowest conc. to agglutinate a 2% suspension of human erythrocytes after 1 hr incubation at 25 °C). Requires Type A Human Blood.
Palavra indicadora
Danger
Frases de perigo
Declarações de precaução
Classificações de perigo
Repr. 2 - Resp. Sens. 1 - Skin Sens. 1
Código de classe de armazenamento
11 - Combustible Solids
Classe de risco de água (WGK)
WGK 3
Ponto de fulgor (°F)
Not applicable
Ponto de fulgor (°C)
Not applicable
Equipamento de proteção individual
dust mask type N95 (US), Eyeshields, Faceshields, Gloves
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