Pular para o conteúdo
Merck
Todas as fotos(1)

Documentos Principais

I1145

Sigma-Aldrich

Interleukin-5 from mouse

≥97% (SDS-PAGE), recombinant, expressed in baculovirus infected Sf21 cells, lyophilized powder, suitable for cell culture

Sinônimo(s):

IL-5

Faça loginpara ver os preços organizacionais e de contrato
Todas as fotos(1)

About This Item

Número MDL:
MFCD00131402
Código UNSPSC:
12352202
NACRES:
NA.32

fonte biológica

mouse

Nível de qualidade

200

recombinante

expressed in baculovirus infected Sf21 cells

Ensaio

≥97% (SDS-PAGE)

Formulário

lyophilized powder

potência

0.04-0.30 ng/mL EC50

peso molecular

45-50 kDa

embalagem

pkg of 5 μg

técnica(s)

cell culture | mammalian: suitable

Impurezas

endotoxin, tested

nº de adesão UniProt

P04401

temperatura de armazenamento

−20°C

Informações sobre genes

mouse ... Il5(16191)

Categorias relacionadas

Ações bioquímicas/fisiológicas

Exhibits activity on eosinophils, B cells, and thymocytes.
Interleukin-5 exhibits activity on eosinophils, B cells, and thymocytes. Human and mouse IL-5 exhibit homology at the nucleotide and amino acid levels and show species cross-reactivity.
Interleukin-5 is a product of activated T lymphocytes and exhibits activity on eosinophils, B cells and thymocytes. Synonyms or biological activities attributed to IL-5 include: EDF (eosinophil differentiating factor), BCGF-II (B cell growth factor-II), TRF (T cell replacing factor), IgA-EF (IgA enhancing factor) and EO-CSF (eosinophil colony stimulating factor). Natural IL-5 is a 45-50 kDa dimeric glycoprotein, although glycosylation is not required for activity. Human and mouse IL-5 exhibit homology at the nucleotide and amino acid levels and show species cross-reactivity.

forma física

Lyophilized from a 0.2 μm filtered solution in phosphate buffered saline containing 0.25 mg bovine serum albumin.

Código de classe de armazenamento

11 - Combustible Solids

Classe de risco de água (WGK)

WGK 3

Ponto de fulgor (°F)

Not applicable

Ponto de fulgor (°C)

Not applicable

Equipamento de proteção individual

Eyeshields, Gloves, type N95 (US)

Escolha uma das versões mais recentes:

Certificados de análise (COA)

Lot/Batch Number
SLBX1157
091M1192V
051M1338V
050M1558
029K1234

Não está vendo a versão correta?

Se precisar de uma versão específica, você pode procurar um certificado específico pelo número do lote ou da remessa.

Pesquise por COA

Já possui este produto?

Encontre a documentação dos produtos que você adquiriu recentemente na biblioteca de documentos.

Visite a Biblioteca de Documentos

Stefan Rebhandl et al.
European journal of immunology, 44(7), 2175-2187 (2014-03-29)
Activation-induced deaminase (AID) is a DNA-mutating enzyme that mediates class-switch recombination as well as somatic hypermutation of antibody genes in B cells. Due to off-target activity, AID is implicated in lymphoma development by introducing genome-wide DNA damage and initiating chromosomal
Yuan Wang et al.
Journal of immunology (Baltimore, Md. : 1950), 195(3), 1171-1181 (2015-06-28)
Complement is implicated in asthma pathogenesis, but its mechanism of action in this disease remains incompletely understood. In this study, we investigated the role of properdin (P), a positive alternative pathway complement regulator, in allergen-induced airway inflammation. Allergen challenge stimulated
Xiang Zhu et al.
American journal of physiology. Gastrointestinal and liver physiology, 306(11), G974-G982 (2014-04-20)
Extracellular acidification has been observed in allergic inflammatory diseases. Recently, we demonstrated that the proton-sensing receptor G protein-coupled receptor 65 (GPR65) regulates eosinophil survival in an acidic environment in vitro and eosinophil accumulation in an allergic lung inflammation model. For
Chisa Nakashima et al.
The Journal of allergy and clinical immunology, 134(1), 100-107 (2014-04-10)
Although eosinophils have been detected in several human skin diseases in the vicinity of basophils, how eosinophils infiltrate the skin and the role of eosinophils in the development of skin inflammation have yet to be examined. Using murine irritant contact

Artigos

Interleukin Family (IL)

The Interleukins comprise a disparate group of cytokines and growth factors that are produced by and released from leukocytes. Interleukin-1β (1L-1β) is released primarily from stimulated macrophages and monocytes and plays a key role in inflammatory and immune responses and may induce anti-tumor immunity.

Nossa equipe de cientistas tem experiência em todas as áreas de pesquisa, incluindo Life Sciences, ciência de materiais, síntese química, cromatografia, química analítica e muitas outras.

Entre em contato com a assistência técnica