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H5659

Sigma-Aldrich

L-Histidina

98.5-101.0%, suitable for cell culture, BioXtra, non-animal source

Sinônimo(s):

Ácido L-α-amino-β-(4-imidazolil)propiônico

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About This Item

Fórmula empírica (Notação de Hill):
C6H9N3O2 · HCl · H2O
Número CAS:
5934-29-2
Peso molecular:
209.63
Beilstein:
4168261
Número MDL:
MFCD00151027
Código UNSPSC:
12352209
eCl@ss:
32160406
ID de substância PubChem:
24895703
NACRES:
NA.26

product name

L-Histidina, from non-animal source, meets EP testing specifications, suitable for cell culture, 98.5-101.0%

fonte biológica

non-animal source

Nível de qualidade

300

Agency

meets EP testing specifications

linha de produto

BioXtra

Ensaio

98.5-101.0%

forma

crystalline powder

técnica(s)

cell culture | mammalian: suitable

Impurezas

endotoxin, tested

cor

white

pf

254 °C (dec.) (lit.)

solubilidade

H2O: 100 mg/mL

cadeia de caracteres SMILES

O.Cl.N[C@@H](Cc1c[nH]cn1)C(O)=O

InChI

1S/C6H9N3O2.ClH.H2O/c7-5(6(10)11)1-4-2-8-3-9-4;;/h2-3,5H,1,7H2,(H,8,9)(H,10,11);1H;1H2/t5-;;/m0../s1

chave InChI

CMXXUDSWGMGYLZ-XRIGFGBMSA-N

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Aplicação

L-Histidine monohydrochloride monohydrate has been used in bee cell culture medium.
L-Histidine monohydrochloride, non-animal, is used in cell culture media formulations used in biomanufacturing. The use of non-animal-sourced L-Histidine and other components avoids the risk of contaminating bioproducts with adventitious viruses.

Ações bioquímicas/fisiológicas

L-Histidine is involved in the one-carbon unit metabolism. It is associated with protein methylation. L-Histidine is a part of hemoglobin structure and function. L-Histidine is a component of dipeptides with antioxidative property. Histidine serves as a precursor for the formation of histamine, which is associated with allergic responses. Urocanic acid, an immune response modulator in skin is also biosynthesised from histidine.

Código de classe de armazenamento

11 - Combustible Solids

Classe de risco de água (WGK)

WGK 1

Ponto de fulgor (°F)

Not applicable

Ponto de fulgor (°C)

Not applicable

Equipamento de proteção individual

Eyeshields, Gloves, type N95 (US)

Certificados de análise (COA)

Busque Certificados de análise (COA) digitando o Número do Lote do produto. Os números de lote e remessa podem ser encontrados no rótulo de um produto após a palavra “Lot” ou “Batch”.

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L-Histidina

SAFC

H3911

L-Histidina

L-Histidina BioUltra, ≥99.5% (NT)

Sigma-Aldrich

53319

L-Histidina

L-Histidine-13C6,15N3 hydrochloride monohydrate ≥98 atom %, 98% (CP)

707848

L-Histidine-13C6,15N3 hydrochloride monohydrate

Medium for development of bee cell cultures (Apis mellifera: Hymenoptera: Apidae).
Hunter WB
In Vitro Cellular & Developmental Biology. Animal, 46(2), 83-86 (2010)
D J Williams et al.
IEE proceedings. Nanobiotechnology, 152(6), 207-210 (2006-01-31)
Tissue engineering and regenerative medicine are interdisciplinary fields that apply principles of engineering and life sciences to develop biological substitutes, typically composed of biological and synthetic components, that restore, maintain or improve tissue function. Many tissue engineering technologies are still
Jean-Christophe Drugmand et al.
Biotechnology advances, 30(5), 1140-1157 (2011-10-11)
Insect cells (IC) and particularly lepidopteran cells are an attractive alternative to mammalian cells for biomanufacturing. Insect cell culture, coupled with the lytic expression capacity of baculovirus expression vector systems (BEVS), constitutes a powerful platform, IC-BEVS, for the abundant and
Yoshihiro Kaneko et al.
Journal of bioscience and bioengineering, 109(3), 274-280 (2010-02-18)
Pharmaceutical manufacturing plants can be operated continuously for several months. It is therefore important to use cells with long-term stability for the production of active ingredients. We investigated the reliability and long-term stability of an antibody-producing cell line. A recombinant
Carlota Diaz Sanchez-Bustamante et al.
Biotechnology and bioengineering, 93(1), 169-180 (2005-10-29)
A precise understanding of processes managing heterologous protein production in vitro and in vivo is essential for the manufacture of sophisticated biopharmaceuticals as well as for future gene therapy and tissue engineering initiatives. Capitalizing on the gravity-enforced self-assembly of monodispersed
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