H6034

L-Histidina

98.5-101.0%, suitable for cell culture, non-animal source, meets EP, USP testing specifications

• Sinônimo(s): NSC 137773, Ácido (S)-2-amino-3-(4-imidazolil)propiônico
• Fórmula empírica (Notação de Hill): C₆H₉N₃O₂
• Número CAS: 71-00-1
• Peso molecular: 155.15
• Beilstein: 84088
• Número CE: 200-745-3
• Número MDL: MFCD00064315
• Código UNSPSC: 12352209
• eCl@ss: 32160406
• ID de substância PubChem: 24895728
• NACRES: NA.26

Propriedades

• product name: L-Histidina, suitable for cell culture, meets EP, USP testing specifications, from non-animal source
• fonte biológica: non-animal source
• Nível de qualidade: 300
• Agency: meets EP testing specifications; meets USP testing specifications
• Ensaio: 98.5-101.0%
• forma: powder
• atividade óptica: [α]20/D 12.0 to 12.8 °, c = 11 in 6 M HCl; [α]25/D 12.6 to 14.0 °, c = 11 in 6 M HCl
• técnica(s): cell culture | mammalian: suitable
• Impurezas: endotoxin, tested
• cor: white to off-white
• pf: 282 °C (dec.) (lit.)
• solubilidade: H₂O: 50 mg/mL
• traços de cátion: As: ≤1 ppm; Fe: ≤10 ppm; NH₄⁺: <0.02%
• aplicação(ões): peptide synthesis; pharmaceutical (small molecule)
• grupo funcional: (Imidazole); amine; carboxylic acid
• temperatura de armazenamento: room temp
• cadeia de caracteres SMILES: N[C@@H](Cc1c[nH]cn1)C(O)=O
• InChI: 1S/C6H9N3O2/c7-5(6(10)11)1-4-2-8-3-9-4/h2-3,5H,1,7H2,(H,8,9)(H,10,11)/t5-/m0/s1
• chave InChI: HNDVDQJCIGZPNO-YFKPBYRVSA-N
• Informações sobre genes: human ... CA1(759) , CA2(760)

Descrição

Descrição geral

L-Histidine is a proteinogenic amino acid and an essential amino acid required for histamine production. This positively charged amino acid is vital for growth, tissue repair, myelin sheath maintenance, and histamine synthesis. Histamine plays critical roles in immunity, gastric secretion, and more. L-Histidine is essential for blood cell production and tissue protection against radiation and heavy metals. L-Histidine plays a role as a metabolite and also acts as a cofactor in enzyme protection during protein synthesis. It is an L-enantiomer of histidine and is necessary for histamine synthesis and human development. L-Histidine finds applications in cell culture, metabolomics and biochemical research.

Aplicação

L-histidine has been used as a component in agar plates containing 5-fluorocytosine (5-FC) for the selection of yeast transformants. It has also been used as a component of adult mouse keratinocyte growth medium.

Ações bioquímicas/fisiológicas

L-Histidine is an essential amino acid that binds to metal ions and may aid in the transport of copper. Histidine is widely present at the active sites of enzymes. It also has a role in binding of heme groups, macromolecules and phosphate groups in the binding sites of proteins.

Precursor da histamina por ação da histidina descarboxilase.

Características e benefícios

• Can be used in Metabolomics and Biochemical research
• High-quality compound suitable for multiple research applications

Outras notas

For additional information on our range of Biochemicals, please complete this form.

Informações de segurança

• Código de classe de armazenamento: 11 - Combustible Solids
• Classe de risco de água (WGK): WGK 1
• Ponto de fulgor (°F): Not applicable
• Ponto de fulgor (°C): Not applicable
• Equipamento de proteção individual: Eyeshields, Gloves, type N95 (US)