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G4921

Sigma-Aldrich

Anti-Granulocyte Colony Stimulating Factor antibody produced in goat

affinity isolated antibody, lyophilized powder

Sinônimo(s):

Anti-G-CSF

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About This Item

Número MDL:
MFCD00211951
Código UNSPSC:
51111800
NACRES:
NA.41

fonte biológica

goat

Nível de qualidade

100

conjugado

unconjugated

forma do anticorpo

affinity isolated antibody

tipo de produto de anticorpo

primary antibodies

clone

polyclonal

Formulário

lyophilized powder

reatividade de espécies

mouse

técnica(s)

neutralization: suitable
western blot: 0.1-0.2 μg/mL

nº de adesão UniProt

P09920

temperatura de armazenamento

−20°C

modificação pós-traducional do alvo

unmodified

Informações sobre genes

mouse ... Csf3(12985)

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Imunogênio

purified, recombinant mouse granulocyte colony stimulating factor, expressed in E. coli.

Ações bioquímicas/fisiológicas

Mature myeloid cells are derived from bone-marrow derived precursor cells by the activity of three colony stimulating factors, granulocyte/macrophage colony-stimulating factor (GM-CSF), macrophage colony-stimulating factor (M-CSF) and granulocyte colony-stimulating factor (G-CSF). The expression of G-CSF is the result of activation of pathways in response to tumor necrosis factor-α, LPS and toll-like receptor ligands. The main functions of G-CSF include the generation of neutrophils and induction of the circulation of hematopoietic stem cells from the bone marrow.

forma física

Lyophilized from a 0.2 μm filtered solution in phosphate buffered saline with 5% trehalose.

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Código de classe de armazenamento

13 - Non Combustible Solids

Classe de risco de água (WGK)

WGK 1

Ponto de fulgor (°F)

Not applicable

Ponto de fulgor (°C)

Not applicable

Equipamento de proteção individual

Eyeshields, Gloves, type N95 (US)

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Certificados de análise (COA)

Lot/Batch Number
MKCL7567
098K0570

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Pesquise por COA

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R R Ji et al.
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The serine/threonine kinase Akt/PKB has been implicated in cell survival signalling in many cell types, including the dorsal root ganglion (DRG). However, little is known about its role in physiological and pathophysiological conditions in the adult sensory and nociceptive system.
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IUBMB life, 62(8), 611-617 (2010-08-04)
The three colony-stimulating factors, granulocyte/macrophage colony-stimulating factor (GM-CSF), macrophage colony-stimulating factor (M-CSF), and granulocyte colony-stimulating factor (G-CSF), have been regarded as immunostimulators because of their role in granulocyte and myeloid hematopoiesis and immune function. However, unlike GM-CSF and M-CSF, G-CSF

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