D4010

2′-Deoxyguanosine 5′-triphosphate sodium salt hydrate

≥96% (HPLC)

• Sinônimo(s): 2′-deoxy-, 5′-triphosphate sodium salt, Guanosine, dGTP sodium salt hydrate
• Fórmula empírica (Notação de Hill): C₁₀H₁₆N₅O₁₃P₃ · xNa⁺ · yH₂O
• CAS Number: 18423-40-0
• Peso molecular: 507.18 (anhydrous free acid basis)
• Número MDL: MFCD01311036
• Código UNSPSC: 41106305
• ID de substância PubChem: 24893806
• NACRES: NA.51

Propriedades

• fonte biológica: synthetic (organic)
• Nível de qualidade: 200
• Ensaio: ≥96% (HPLC)
• Formulário: powder
• Condições de expedição: dry ice
• temperatura de armazenamento: −20°C

Descrição

Aplicação

2′-Deoxyguanosine 5′-triphosphate sodium salt hydrate has been used:

• as a component in a polymerase chain reaction (PCR) mixture for PCR product formation using AM-toxin primers
• as an internal standard to improve the analytical performance of capillary electrophoresis (CE) analysis for the evaluation of the cleanup process
• as a putative substrate in in vitro enzyme activity assay to incubate with nudix hydrolase 15 (NUDT15) protein for the evaluation of putative NUDT15 inhibitors

Ações bioquímicas/fisiológicas

Deoxyguanosine 5′-triphosphate (dGTP), a purine deoxynucleotide, is a substrate of DNA polymerase(s) and reverse transcriptases. dGTP is useful to study the distribution, specificity, and kinetics of various nucleoside-triphosphatases (NTPase) and ribonucleotide reductases.

Informações de segurança

• Código de classe de armazenamento: 11 - Combustible Solids
• Classe de risco de água (WGK): WGK 3
• Equipamento de proteção individual: Eyeshields, Gloves, type N95 (US)