D4010
2′-Deoxyguanosine 5′-triphosphate sodium salt hydrate
≥96% (HPLC)
Sinônimo(s):
2′-deoxy-, 5′-triphosphate sodium salt, Guanosine, dGTP sodium salt hydrate
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About This Item
Produtos recomendados
fonte biológica
synthetic (organic)
Nível de qualidade
Ensaio
≥96% (HPLC)
Formulário
powder
Condições de expedição
dry ice
temperatura de armazenamento
−20°C
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Categorias relacionadas
Aplicação
2′-Deoxyguanosine 5′-triphosphate sodium salt hydrate has been used:
- as a component in a polymerase chain reaction (PCR) mixture for PCR product formation using AM-toxin primers
- as an internal standard to improve the analytical performance of capillary electrophoresis (CE) analysis for the evaluation of the cleanup process
- as a putative substrate in in vitro enzyme activity assay to incubate with nudix hydrolase 15 (NUDT15) protein for the evaluation of putative NUDT15 inhibitors
Ações bioquímicas/fisiológicas
Deoxyguanosine 5′-triphosphate (dGTP), a purine deoxynucleotide, is a substrate of DNA polymerase(s) and reverse transcriptases. dGTP is useful to study the distribution, specificity, and kinetics of various nucleoside-triphosphatases (NTPase) and ribonucleotide reductases.
Código de classe de armazenamento
11 - Combustible Solids
Classe de risco de água (WGK)
WGK 3
Equipamento de proteção individual
Eyeshields, Gloves, type N95 (US)
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Human ribonucleotide reductases (hRNRs) catalyze the conversion of nucleotides to deoxynucleotides and are composed of α- and β-subunits that form active α(n)β(m) (n, m = 2 or 6) complexes. α binds NDP substrates (CDP, UDP, ADP, and GDP, C site)
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