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C8534

Sigma-Aldrich

Anti-Chorionic Gonadotropin (α+β subunits) (HCG) antibody produced in rabbit

whole antiserum

Sinônimo(s):

Chorionic Gonadotropin Antibody, HCG Antibody - Anti-Chorionic Gonadotropin (α+β subunits) (HCG) antibody produced in rabbit, Hcg Antibodies, Hcg Antibody

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About This Item

Número MDL:
Código UNSPSC:
12352203
NACRES:
NA.41

fonte biológica

rabbit

Nível de qualidade

conjugado

unconjugated

forma do anticorpo

whole antiserum

tipo de produto de anticorpo

primary antibodies

clone

polyclonal

contém

15 mM sodium azide

reatividade de espécies

human

técnica(s)

immunohistochemistry: 1:100 using human placental tissue
radioimmunoassay: 1:50,000

nº de adesão UniProt

temperatura de armazenamento

−20°C

modificação pós-traducional do alvo

unmodified

Informações sobre genes

Descrição geral

Human Chorionic Gonadotropin (HCG) is a hormone detected in the blood and urine during pregnancy. The peak levels of HCG are detected around Week 12 of gestation and diminish during remaining period of pregnancy. HCG is composed of α and β subunits. There are five variants of HCG that have been identified; HCG, hyperglycosylated HCG, sulphated HCG, free β subunit and pituitary HCG. The important functions of HCG include implantation, angiogenesis, progesterone production, regulation of immune cells and cytotrophoblast differentiation and development of placenta
Anti-Chorionic Gonadotropin (α + α subunits) antibody is specific for both α and β subunits of human chorionic gonadotropin.

Imunogênio

HCG

Aplicação

Anti-Chorionic Gonadotropin (α + α subunits) antibody may be used for RIA at a minimum working dilution of 1:50,000. For immunohistochemistry, the recommended working dilution is 1:100-1:200. The antibody was also used for immunofluorescence at a working dilution of 1:50 and for ELISA.

Reconstituição

Dilute with buffer: 0.01 M phosphate, pH 7.8, 0.15 M sodium chloride, 0.5% bovine serum albumin and 0.1 sodium azide.

Exoneração de responsabilidade

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

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Código de classe de armazenamento

10 - Combustible liquids

Classe de risco de água (WGK)

WGK 3

Ponto de fulgor (°F)

Not applicable

Ponto de fulgor (°C)

Not applicable

Equipamento de proteção individual

Eyeshields, Gloves, multi-purpose combination respirator cartridge (US)


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Biological functions of hCG and hCG-related molecules
Cole LA
Reproductive Biology and Endocrinology, 8, doi: 10-doi: 10 (2010)
hCG, the wonder of today's science
Cole LA
Reproductive Biology and Endocrinology, 10, doi: 10-doi: 10 (2010)
W Norris et al.
Placenta, 32 Suppl 2, S182-S185 (2011-02-08)
Human chorionic gonadotropin (hCG) is crucial for successful pregnancy. Its many functions include angiogenesis and immune regulation. Despite years of research, the etiology of preeclampsia remains unknown. Marked by insufficient trophoblast invasion and poor spiral artery remodeling, preeclampsia has also
Rui Zhao et al.
Oncology letters, 16(4), 4271-4278 (2018-09-11)
Hormones and their receptors affect the development process of gastric cancer. Previous studies have revealed that human chorionic gonadotropin (hCG) is expressed in gastric cancer tissue. However, the mechanism by which hCG exerts its effects on gastric cancer cells had
Anupam Basu et al.
Analytical biochemistry, 366(2), 175-181 (2007-06-02)
The development of a simultaneous multianalyte immunoassay for the detection of progesterone and human chorionic gonadotropin (hCG) in serum is described. In this simultaneous multianalyte assay, two different enzymes, viz. horse radish peroxidase (HRP) and alkaline phosphatase (ALP), were used

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