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Merck
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Key Documents

C6003

Sigma-Aldrich

Chlorophyllin sodium copper salt

commercial grade, powder

Sinônimo(s):

Chlorophyllin, coppered trisodium salt

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About This Item

Fórmula empírica (Notação de Hill):
C34H31CuN4Na3O6
Número CAS:
Peso molecular:
724.15
Número CE:
Código UNSPSC:
12171500
ID de substância PubChem:
NACRES:
NA.47

product name

Chlorophyllin sodium copper salt, commercial grade

grau

commercial grade

Nível de qualidade

forma

powder

cor

black
green to very dark green

solubilidade

H2O: 100 mg/mL, dark green

aplicação(ões)

diagnostic assay manufacturing
hematology
histology

temperatura de armazenamento

2-8°C

cadeia de caracteres SMILES

[Na+].[Na+].[Na+].CCc1c(C)c2cc3c(C=C)c(C)c4cc5nc(C(CCC([O-])=O)C5C)c(CC([O-])=O)c6c(C([O-])=O)c(C)c(cc1n2)n6[Cu]n34

InChI

1S/C34H36N4O6.Cu.3Na/c1-7-19-15(3)23-12-25-17(5)21(9-10-29(39)40)32(37-25)22(11-30(41)42)33-31(34(43)44)18(6)26(38-33)14-28-20(8-2)16(4)24(36-28)13-27(19)35-23;;;;/h7,12-14,17,21H,1,8-11H2,2-6H3,(H5,35,36,37,38,39,40,41,42,43,44);;;;/q;+2;3*+1/p-5

chave InChI

HWDGVJUIHRPKFR-UHFFFAOYSA-I

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Aplicação

Chlorophyllin sodium copper salt has been used to study the effect of chlorophyllin against radiation-induced hematopoietic syndrome. It has been used to study the effect of chlorophyllin on the excretion of PhIP (2-amino-1-methyl-6-phenylimidazo[4,5-b]pyridine) and its metabolites into the breast-milk of lactating rats.

Ações bioquímicas/fisiológicas

Chlorophyllin is a water soluble derivative of chlorophyll. It has chemopreventive properties and forms a non-covalent complex with many mutagenic/carcinogenic molecules. The complex formation reduces absorption or allows excretion of the mutagenic/carcinogenic molecules. Chlorophyllin also exhibits antioxidant, antiapoptotic and immunostimulatory effects. It provides benefits, such as prevention of body odor and increased wound healing.

Código de classe de armazenamento

11 - Combustible Solids

Classe de risco de água (WGK)

WGK 2

Ponto de fulgor (°F)

Not applicable

Ponto de fulgor (°C)

Not applicable

Equipamento de proteção individual

Eyeshields, Gloves, type N95 (US)


Certificados de análise (COA)

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Jun Zhang et al.
The Analyst, 137(18), 4287-4294 (2012-08-02)
The human hepatoma 3B cell line was chosen as an experimental model for in vitro test of drug screening. The drugs included chlorophyllin and its derivatives such as fluo-chlorophyllin, sodium copper chlorophyllin, and sodium iron chlorophyllin. The 3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyl-tetrazolium bromide (MTT)
S Wohllebe et al.
Parasitology research, 111(2), 729-733 (2012-04-06)
Tests were conducted to determine the efficiency of the photodynamic substance chlorophyllin to kill different life stages of the protozoan parasite Ichthyophthirius mulftifiliis (Fouquet) which causes the white spot disease in many freshwater fish species. This study has developed a
Yuwei Guo et al.
Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy, 79(5), 1099-1104 (2011-05-31)
In order to examine the mechanism and process of sonodynamic reaction, the chlorophyllin magnesium (Chl-Mg) acting as a sonosensitizer was irradiated by ultrasound, and the generation of reactive oxygen species (ROS) were detected by the method of oxidation-extraction spectrometry (OES).
Siddavaram Nagini et al.
Cellular oncology (Dordrecht), 35(5), 385-395 (2012-09-18)
Chlorophyllin, a water soluble semi-synthetic food-grade derivative is reported to exhibit a wide range of beneficial health effects. We investigated the effect of chlorophyllin supplementation on Wnt/β-catenin and vascular endothelial growth factor (VEGF) signaling in the 7,12-dimethylbenz[a]anthracene (DMBA)-induced hamster buccal
Stephanie Wohllebe et al.
Photochemistry and photobiology, 87(5), 1113-1122 (2011-06-28)
Chlorophyllin kills mosquito larvae (Culex, Aedes) in the aquatic habitat at low concentrations via photodynamic reactions under irradiation. The effects of chlorophyllin were investigated at the cellular level using the transparent larvae of Chaoborus crystallinus as a model system. Their

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