B5150

Bacitracin zinc salt

from Bacillus licheniformis, ~70,000 U/g

• Sinônimo(s): Zinc bacitracin
• Fórmula empírica (Notação de Hill): C₆₆H₁₀₁N₁₇O₁₆SZn
• Número CAS: 1405-89-6
• Peso molecular: 1486.07
• Número CE: 215-787-8
• Número MDL: MFCD00130598
• Código UNSPSC: 51282002
• ID de substância PubChem: 57653938
• NACRES: NA.85

Propriedades

• fonte biológica: Bacillus licheniformis
• Nível de qualidade: 200
• forma: powder
• atividade específica: ~70,000 U/g
• pf: 250 °C (dec.) (lit.)
• espectro de atividade do antibiótico: Gram-positive bacteria
• Modo de ação: cell wall synthesis | interferes
• temperatura de armazenamento: 2-8°C
• cadeia de caracteres SMILES: [Zn++].CCC(C)C(N)C1=NCC(S1)C(=O)N[C@@H](CC(C)C)C(=O)N[C@H](CCC([O-])=O)C(=O)N[C@@H]([C@@H](C)CC)C(=O)N[C@H]2CCCCNC(=O)[C@H](CC(N)=O)NC(=O)[C@@H](CC([O-])=O)NC(=O)[C@H](Cc3cnc[nH]3)NC(=O)[C@@H](Cc4ccccc4)NC(=O)[C@@H](NC(=O)[C@@H](CCCN)NC2=O)[C@@H](C)CC
• InChI: 1S/C66H103N17O16S.Zn/c1-9-35(6)52(69)66-72-32-48(100-66)63(97)80-43(26-34(4)5)59(93)75-42(22-23-50(85)86)58(92)83-53(36(7)10-2)64(98)76-40-20-15-16-25-71-55(89)46(29-49(68)84)78-62(96)47(30-51(87)88)79-61(95)45(28-39-31-70-33-73-39)77-60(94)44(27-38-18-13-12-14-19-38)81-65(99)54(37(8)11-3)82-57(91)41(21-17-24-67)74-56(40)90;/h12-14,18-19,31,33-37,40-48,52-54H,9-11,15-17,20-30,32,67,69H2,1-8H3,(H2,68,84)(H,70,73)(H,71,89)(H,74,90)(H,75,93)(H,76,98)(H,77,94)(H,78,96)(H,79,95)(H,80,97)(H,81,99)(H,82,91)(H,83,92)(H,85,86)(H,87,88);/q;+2/p-2/t35?,36-,37-,40-,41+,42+,43-,44+,45-,46-,47+,48?,52?,53-,54-;/m0./s1
• chave InChI: NKULICGUDKGGRL-FCHFGNCGSA-L

Descrição

Descrição geral

Chemical structure: peptide

Aplicação

Bacitracin zinc salt is a peptide antibiotic used to study dysruption of bacterial cell wall synthesis at the level of peptidoglycan biosynthesis and isoprenyl metabolism. It is used to study the biosynthesis of sterols and squalene.

Ações bioquímicas/fisiológicas

Bacitracin is a protease inhibitor. Antimicrobial spectrum: Gram-positive bacteria.
Mode of Action: Inhibits bacterial cell wall synthesis by inhibiting dephosphorylation of lipid pyrophosphate.

Outras notas

Keep container tightly closed in a dry and well-ventilated place.

Informações de segurança

• Código de classe de armazenamento: 11 - Combustible Solids
• Classe de risco de água (WGK): WGK 3
• Ponto de fulgor (°F): Not applicable
• Ponto de fulgor (°C): Not applicable
• Equipamento de proteção individual: Eyeshields, Gloves, type N95 (US)