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Merck
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Key Documents

31626

Supelco

Bacitracin A

VETRANAL®, analytical standard, main stereoisomer ~50 %

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About This Item

Fórmula empírica (Notação de Hill):
C66H103N17O16S
Peso molecular:
1422.69
Número CE:
Código UNSPSC:
41116107
ID de substância PubChem:
Número E:
E700
NACRES:
NA.24

grau

analytical standard

Nível de qualidade

linha de produto

VETRANAL®

prazo de validade

limited shelf life, expiry date on the label

composição

main stereoisomer, ~50%

técnica(s)

HPLC: suitable
gas chromatography (GC): suitable

aplicação(ões)

cleaning products
cosmetics
food and beverages
personal care

formato

neat

temperatura de armazenamento

2-8°C

cadeia de caracteres SMILES

CC[C@H](C)[C@H](N)C1=N[C@@H](CS1)C(=O)N[C@@H](CC(C)C)C(=O)N[C@H](CCC(O)=O)C(=O)NC([C@@H](C)CC)C(=O)N[C@H]2CCCCNC(=O)[C@H](CC(N)=O)NC(=O)[C@@H](CC(O)=O)NC(=O)[C@H](Cc3cnc[nH]3)NC(=O)[C@@H](Cc4ccccc4)NC(=O)C(NC(=O)[C@@H](CCCN)NC2=O)[C@@H](C)CC

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Descrição geral

Bacitracin is a polypeptide antibiotic produced by strains of Bacillus subtilis and Bacillus licheniformis. Bacitracin A is a commercially produced, major microbiologically active component of bacitracin.

Aplicação

Commission Regulation (EU) No 37/2010 of 22 December 2009 on pharmacologically active substances and their classification regarding maximum residue limits in foodstuffs of animal origin
Refer to the product′s Certificate of Analysis for more information on a suitable instrument technique. Contact Technical Service for further support.

Informações legais

VETRANAL is a registered trademark of Merck KGaA, Darmstadt, Germany

Código de classe de armazenamento

11 - Combustible Solids

Classe de risco de água (WGK)

WGK 3

Equipamento de proteção individual

Eyeshields, Gloves, type N95 (US)


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Enhancement of precursor amino acid supplies for improving bacitracin production by activation of branched chain amino acid transporter BrnQ and deletion of its regulator gene lrp in Bacillus licheniformis.
Zhu J, et al.
Synthetic and systems biotechnology, 3(4), 236-243 (2018)
G J Quinlan et al.
Biochemical pharmacology, 42(8), 1595-1599 (1991-09-27)
Several antibacterial antibiotics have been shown to participate with transition metal ions in chemical reactions leading to the formation of reactive oxygen species. An important host defence mechanism for dealing with invading bacteria involves the production of reactive oxygen species
Harjodh Singh et al.
Scientific reports, 9(1), 11561-11561 (2019-08-11)
Antibiotic-resistance is ever growing burden on our society for the past many years. Many synthetic chemistry approaches and rational drug-design have been unable to pace up and tackle this problem. Natural resources, more specifically, the microbial diversity, on the other
L W Tetler et al.
Biological mass spectrometry, 22(12), 712-720 (1993-12-01)
Bacitracin is a mixture of polypeptide antibiotics produced by the action of Bacillus subtilis and Bacillus licheniformis. The mixture has previously been shown to contain at least ten components, of which only the major component, Bacitracin A, and its oxidized
M M Siegel et al.
Biological mass spectrometry, 23(4), 186-204 (1994-04-01)
The bacitracin antibiotic complex consists principally of bacitracin A, a peptide antibiotic containing seven amino acid residues in a ring and five amino acid residues in a blocked side chain, together with a mixture of minor components presumably related but

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